Autoantibodies Flashcards

1
Q

Anti-Ach

A

Myasthenia gravis

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2
Q

Anti-basement membrane

A

Goodpasture

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3
Q

Anticardiolipin, lupus anticoagulant

A

SLE, antiphospholipid syndrome

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4
Q

Anticentromere

A

Limited scleroderma (CREST)

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5
Q

Anti-demoglein (anti-desmosome)

A

Pemphigus vulgaris

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6
Q

Anti-dsDNA, anti-Smith

A

SLE

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7
Q

Anti-glutamic acid decarboxylase (GAD-65)

A

T1DM

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8
Q

Antihemidesmosome

A

Bullous pemphigoid

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9
Q

Anti-histone

A

Drug-induced lupus

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10
Q

Anti-Jo1, anti SRM, anti Mi2

A

Polymyositis, dermatomyositis

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11
Q

Antimitochondrial

A

PBC

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12
Q

Antinuclear

A

SLE, nonspecific

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13
Q

Antipariental cell

A

Pernicious anemia

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14
Q

Antiphospholipase A2 R

A

1 membranous nephropathy

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15
Q

Anti-Scl-70 (anti-DNA topoisomerase I)

A

Scleroderma (diffuse)

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16
Q

Anti-smooth muscle

A

Autoimmune hepatitis type 1

17
Q

Anti-SSA, anti-SSB (antiRo, antiLa)

A

Sjogrens syndrome

18
Q

Anti-TSH R

A

Graves disease

19
Q

Anti U1 RNA (ribonucleoprotein)

A

Mixed CT disorder

20
Q

Voltage gated Ca channel AB

A

Lambert-Eaton syndrome

21
Q

IgA anti-endomysial, IgA anti-tissue translutaminase

A

Celiac disease

22
Q

MPO-ANCA/p-ANCA

A

Microscopic polyangitis, eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome)

23
Q

PR3-ANCA/c-ANCA

A

Granulomatous with polyangiitis (Wedgners)

24
Q

Rheumatoid factors (IgM antibody that targets IgG Fc region), anti-CCP (more specific)

A

Rheumatoid arthritis