Electron Transport Chain

Question 1

List the components of electron transport chain

Answer 1

4 enzyme complexes formed of several proteins
Electron carriers
ATP synthase complex

Question 2

List the election carriers

Answer 2

Coenzyme Q
Fes
Cytochromes

Question 3

Explain Coenzyme Q

Answer 3

Fat soluble, mobile molecule between complex I, II, III → it gives electrons one by one

Question 4

Explain fes

Answer 4

Found in all complexes
Transfer electrons

Question 5

Explain cytochromes

Answer 5

Hemoproteins that take electrons one by one and give to oxygen
Fe ion alternate between Fe++ and Fe+++

Question 6

Explain the ATP synthase complex

Answer 6

catalyze phosphorylation of ADP to ATP

Question 7

List the complex 1 inhibitors

Answer 7

Amytal
Rotenone
Mercurials

Question 8

List complex 2 inhibitors

Answer 8

Malonate
Carboxin

Question 9

List the complex 3 inhibitor

Answer 9

Antimyecin

Question 10

List the complex 4 inhibitors

Answer 10

Cyanide
Azide
Carbon monoxide

Question 11

What is the difference between inhibitors of complexes and uncouplers

Answer 11

Inhibitors of complexes - inhibit both oxidation and phosphorylation
Uncouplers - inhibit phosphorylation but not oxidation

Question 12

What happens when ATP synthesis is blocked

Answer 12

Chemical energy will be stoped and replaced by heat release (thermal energy)

Question 13

List the uncouplers

Answer 13

Dinitrophenol
Halothane
Snake venom
Bilirubin

Question 14

Uncouplers interfere with what

Answer 14

Electro chemical gradient

Question 15

What is the inhibitor of ATP synthase complex

Answer 15

Oligomycin

Question 16

What is an example and function of physiological uncouplers

Answer 16

Thermogenin - provides an alternative path for protons instead of return to the matrix passing through ATP synthase