Electrolytes And Fluid Balance Flashcards
What is the chemical formula for water?
H2O
What shape do water molecules have?
‘V’ shape
What is the bond angle in a water molecule?
104.45°
What is the bond length of the hydrogen-oxygen bond in water?
95.84 pm
What is the electronegativity of oxygen and nitrogen?
High
Electronegativity refers to the attraction of electrons by an atom.
What is the electronegativity of hydrogen and carbon?
Low
Electronegativity indicates how strongly an atom can attract electrons.
What charge does oxygen carry in a molecule?
Partial negative charge
This indicates that oxygen attracts electrons more strongly than hydrogen.
What charge do hydrogen atoms carry in a molecule?
Partial positive charge
This indicates that hydrogen atoms have a weaker attraction for electrons compared to oxygen.
Electrons are pulled toward which element in a water molecule?
Oxygen
This results in a polar covalent bond where oxygen is partially negative and hydrogen is partially positive.
What type of attraction occurs between polar molecules?
Hydrogen bonds
Polar molecules attract through oppositely charged poles.
What is the non-covalent attraction between polar water molecules called?
Hydrogen Bonding
This describes the interaction that occurs due to the polarity of water.
What is the charge distribution in water molecules?
Water molecules have a slight negative charge around the oxygen atom and a slight positive charge around the hydrogen atoms.
What type of bonding occurs between water molecules due to their charge distribution?
Hydrogen bonding.
Why do water molecules organize themselves in a specific way?
Because of the slight charges and the attraction between opposites.
Fill in the blank: Water molecules have a slight _______ charge around the oxygen atom.
negative
Fill in the blank: Water molecules have a slight _______ charge around the hydrogen atoms.
positive
True or False: Opposite charges in water molecules repel each other.
False
What is the dissociation equation of a water molecule?
H2O → H+ + OH-
This equation represents the process by which water molecules split into hydrogen ions and hydroxide ions.
How often do water molecules dissociate?
One in every 10 million water molecules
This indicates a very low rate of dissociation in pure water.
What is the concentration of H+ ions in neutral water?
1 x 10^-7
This concentration corresponds to a neutral pH level of 7.
What is the pH level of pure water?
7
A pH of 7 indicates that the solution is neutral, neither acidic nor basic.
Fill in the blank: The ions produced from the dissociation of water are _______ and _______.
H+ and OH-
These ions are crucial for understanding acid-base chemistry in solutions.
What percentage of a 160-lb man is made up of water?
45-75 percent
This range indicates that water constitutes a significant portion of body weight.
How much water is in a 160-lb man?
99 lbs
This is the approximate amount of water in a typical male of this weight.
What factors influence water levels in the human body?
Multiple factors including age, sex, body composition, and physical activity
These factors can affect hydration status and overall fluid balance.
How much protein is in a 160-lb man?
27 lbs
Protein is a crucial component of body mass and contributes to various physiological functions.
How much fat is in a 160-lb man?
24 lbs
This amount reflects the energy storage and insulation functions of fat in the body.
How much do minerals and glycogen weigh in a 160-lb man?
70 lbs
Minerals and glycogen are essential for metabolic processes and maintaining fluid balance.
What percentage of the body composition is water?
60%
Water is the primary component of body composition.
What are the main components of body composition and their percentages?
- 60% water
- 20% lipids
- 15% proteins
- 5% glucose and minerals
These percentages indicate the distribution of different substances in the body.
What percentage of fat is comprised of water?
Around 10%
This indicates that fat tissue contains a small amount of water.
What is the water content of well-hydrated muscles?
75% H2O
Well-hydrated muscles have a high percentage of water, which is crucial for their function.
What percentage of bones is made up of water?
32% H2O
Bones also contain a significant amount of water, contributing to their structure.
What is the water content of blood?
93% H2O
Blood has a very high water content, essential for its function in the body.
True or False: Higher muscle mass correlates with lower water contribution to total body mass.
False
Higher muscle mass and lower fat mass lead to a higher contribution of water to total body mass.
What are the major fluid compartments in the body?
2/3 Intracellular fluid (ICF) and 1/3 Extracellular fluid (ECF)
Extracellular fluid (ECF) includes interstitial fluid, plasma, and digestive juices.
What percentage of body fluid is intracellular fluid (ICF)?
2/3
What percentage of body fluid is extracellular fluid (ECF)?
1/3
Name the components of extracellular fluid (ECF).
- Interstitial fluid
- Plasma
- Digestive juices
Fill in the blank: The major fluid compartment that accounts for 2/3 of body fluid is _______.
Intracellular fluid (ICF)
Fill in the blank: The major fluid compartment that accounts for 1/3 of body fluid is _______.
Extracellular fluid (ECF)
What is the role of electrolytes in fluid balance?
Electrolytes help maintain a delicate equilibrium in fluid balance.
Define cation.
Cation is a positively charged ion.
Define anion.
Anion is a negatively charged ion.
What happens when salts like NaCl dissolve in water?
They come apart and form free electrically charged ions.
Fill in the blank: Chloride ion is represented as _______.
Cl⁻
Fill in the blank: Sodium ion is represented as _______.
Na⁺
True or False: Sodium ions are negatively charged.
False
True or False: Anions are positively charged ions.
False
What is the chemical formula for table salt?
NaCl
What are the two main components that maintain fluid balance in the body?
Electrolytes and water
Electrolytes are minerals that carry an electric charge and are essential for various bodily functions.
What does ECF stand for?
Extracellular Fluid
ECF is the fluid found outside of cells, which includes interstitial fluid and blood plasma.
Which electrolyte is represented by the symbol Na+?
Sodium
Sodium is crucial for maintaining fluid balance and is primarily found in extracellular fluid.
Which electrolyte is represented by the symbol K+?
Potassium
Potassium is essential for cellular function and is predominantly found in intracellular fluid.
Which electrolyte is represented by the symbol Ca2+?
Calcium
Calcium plays a vital role in muscle contraction, nerve transmission, and blood clotting.
Which electrolyte is represented by the symbol Mg2+?
Magnesium
Magnesium is involved in numerous biochemical reactions in the body, including energy production.
Which electrolyte is represented by the symbol Cl-?
Chloride
Chloride helps maintain osmotic pressure and is a component of gastric acid.
Which electrolyte is represented by the symbol HCO3-?
Bicarbonate
Bicarbonate acts as a buffer to maintain pH balance in the body.
Which electrolyte is represented by the symbol HPO4?
Phosphate
Phosphate is important for energy transfer and is a component of DNA and RNA.
What is osmosis?
Movement of a solvent through a semipermeable membrane from low solute to high solute concentration until concentrations on both sides are the same
This process is essential for maintaining fluid balance in cells.
What happens when the concentrations of solute particles are the same on both sides of a cell membrane?
Water flows equally both into and out of the cell
This condition is known as isotonic equilibrium.
What occurs when the concentration inside the cell is greater than outside the cell?
Water flows into the cell to equalize the concentration
This can lead to cell swelling.
What happens when the concentration outside the cell is greater than inside the cell?
Water flows out of the cell to equalize the concentration
This can lead to cell shrinkage.
What is the role of Na+ in cellular fluid balance?
As Na+ moves out of the cell, it increases extracellular Na+ concentration.
This process causes water to move out of the cell to equalize Na+ concentrations.
What happens when a cell begins to swell?
It activates the Na+-K+ pump, moving Na+ out of the cell.
This is a response mechanism to maintain osmotic balance.
Describe the function of the sodium-potassium pump.
Na+ binds to a receptor site on the protein pump, ATP energy changes the protein’s shape, expelling Na+ outside, while K+ binds to another site, causing K+ to be expelled into the cell.
This mechanism is crucial for maintaining the electrochemical gradient across the cell membrane.
Fill in the blank: Water moves out of the cell to equalize _______ concentrations.
Na+
What initiates the movement of Na+ out of the cell?
The activation of the Na+-K+ pump due to cell swelling.
This process helps prevent excessive swelling and maintains homeostasis.
True or False: The sodium-potassium pump requires energy from ATP.
True
What does osmotic pressure refer to in relation to cell function?
The pressure that drives water movement across the cell membrane to balance solute concentrations.
It is a critical factor in maintaining cell shape and function.
What are the key ions involved in the sodium-potassium pump?
- Na+
- K+
These ions are essential for various cellular processes, including nerve impulse transmission and muscle contraction.
Fill in the blank: Na+ is expelled to the _______ of the cell during the pump’s action.
outside
What triggers the shape change in the sodium-potassium pump?
The binding of Na+ and K+ ions.
This shape change is essential for the transport of these ions across the membrane.
What is heat capacity?
The amount of energy required to raise the temperature by 1 degree Celsius
Heat capacity is a critical property in understanding how substances respond to heat.
How does the heat capacity of water compare to that of iron?
Water has 3X the heat capacity of iron
This means water can store more heat energy without a significant change in temperature.
What does a high heat capacity imply for substances?
More energy is required to cool substances with high heat capacity
This property is crucial for regulating temperature in biological systems.
What is a significant implication of water’s high heat capacity for the human body?
It takes a lot of heat to change the temperature of the body
This helps maintain stable internal body temperatures despite external changes.
What triggers the body’s cooling system?
Rise in body temperature
What happens to blood vessels when the body cools down?
Blood vessels dilate
What process begins to help cool the body?
Sweating
What happens to perspiration to aid in cooling?
Perspiration evaporates
What factor affects the body’s cooling ability?
Humidity
What is the pH scale range?
0 - 14
What does maintaining pH balance do?
It maintains pH balance in the body.
What happens if pH balance is not maintained?
Disruption of bodily functions.
What are the components involved in pH balance?
- Carbon dioxide
- Water
- Carbonic acid
- Bicarbonate
What is one function of water related to nutrients?
Dissolves Nutrients: ions, sugars, amino acids, water soluble vitamins
Water is essential for the absorption and transport of essential nutrients in the body.
How does water contribute to nutrient transportation?
Transports Nutrients: Delivers glucose to cells for energy / transports waste product (urea in urine)
Water plays a crucial role in the circulatory system by helping to deliver nutrients and remove waste.
What is one function of water in metabolism?
Provides aqueous environment for metabolism
Water is essential for various metabolic processes to occur effectively.
How does water participate in metabolic reactions?
As a substrate and a product
Water can be involved as a reactant in biochemical reactions and can also be produced as a byproduct.
What is one function of water related to body tissues?
Protection and lubrication of body tissues
Water serves multiple roles in the body, including acting as a lubricant in various fluids.
What fluid protects the brain and spinal cord from shock?
Cerebrospinal fluid
This fluid acts as a cushion for the central nervous system.
What is the purpose of amniotic fluid?
Shock absorber surrounding the growing foetus
Amniotic fluid provides a protective environment for the developing fetus.
What type of fluid is found around joints to facilitate movement?
Synovial fluid
Synovial fluid reduces friction between joint surfaces.
Which body fluid lubricates food during digestion?
Saliva
Saliva contains enzymes that aid in the digestion process.
What is the function of tears in the body?
Lubricate and cleanse the eyes
Tears help maintain eye health by providing moisture and removing debris.
What is included in adequate water intake?
Drinking water, beverages, and food
Adequate water intake encompasses all sources of hydration.
What is the daily fluid intake recommendation for women?
2.0 litres of fluid/day (8 glasses)
This is the general guideline for women’s hydration needs.
What is the daily fluid intake recommendation for men?
2.5 litres fluid/day (10 glasses)
This reflects the higher hydration needs of men compared to women.
How much additional fluid is recommended for pregnant women?
+300 ml/day
This increase accounts for the hydration needs during pregnancy.
How much additional fluid is recommended for lactating women?
+700 ml/day
This increase is necessary to support milk production during lactation.
Who has higher fluid intake recommendations?
Pregnant women, lactating women, athletes and active people
These groups require more hydration due to increased physical demands or physiological changes.
What is the total fluid daily turnover?
2500ml
This includes both fluid intake and output.
What is the fluid intake from metabolic processes?
350ml
This refers to the water produced from metabolic reactions.
What is the fluid intake from fluids consumed?
1200ml
This includes all liquids ingested throughout the day.
What is the water content of foods contributing to fluid intake?
1000ml
This encompasses water obtained from solid food sources.
What is the total fluid output?
2500ml
This includes all forms of fluid loss from the body.
How much fluid is lost through expired air?
350ml
This is the water vapor lost during respiration.
What is the amount of fluid lost through skin/sweat?
850ml
This includes both insensible loss and sweat.
What is the faecal loss of fluid?
100ml
This is the amount of water lost in solid waste.
What is the urine output in terms of fluid loss?
1200ml
This is the volume of water excreted via urine.
What is the moisture content range of raw pork?
53-60%
Moisture content varies based on the cut and preparation of the pork.
What is the moisture content range of cherries?
50-70%
Cherries are high in water content, making them hydrating fruits.
What is the moisture content of avocados?
74%
Avocados are known for their healthy fats but also contain significant water.
What is the moisture content range of chicken?
65-81%
The moisture content can differ depending on the part of the chicken and whether the skin is included.
What is the moisture content range for asparagus?
90-95%
Asparagus has one of the highest water contents among vegetables.
What is the moisture content range of broccoli?
85-90%
Broccoli is both nutritious and hydrating due to its high water content.
What is the moisture content range for bananas?
90-95%
Bananas are a popular fruit with a high water percentage.
What is the moisture content range for fish?
74-80%
Fish muscle proteins have a considerable water content, contributing to their texture.
What is the moisture content range for raw retail cuts of beef?
85-90%
Moisture content can vary based on the cut and preparation method.
What is the moisture content range for lettuce?
90-95%
Lettuce is often used in salads due to its crisp texture and high water content.
Fill in the blank: The moisture content of _______ is 80-85%.
chicken, all classes, raw meat without skin
Fill in the blank: The moisture content of _______ is 50-70%.
cherries
True or False: Avocados have a moisture content of 74%.
True
True or False: Broccoli has a lower moisture content than chicken.
False
What are the main components of the kidney?
Cortex, Medulla, Renal pelvis
These structures play essential roles in kidney function.
What is the function of the kidneys?
Excrete waste products
Waste products include ammonia, uric acid, urea, and creatinine.
What waste products do the kidneys excrete?
- Ammonia
- Uric acid
- Urea
- Creatinine
These substances are filtered out of the blood.
How do the kidneys filter waste products?
Via filtration
This process occurs in the nephrons.
What is the role of nephrons in the kidneys?
Filter waste products
Nephrons are the functional units of the kidney.
What is the renal artery’s function?
Carry blood to the kidneys
It supplies oxygenated blood to the renal tissues.
What is the role of the renal vein?
Carry blood away from the kidneys
It transports deoxygenated blood back to the heart.
What is the purpose of the ureter?
Transport urine from the kidneys to the bladder
Each kidney has one ureter.
Fill in the blank: The renal _______ collects urine from the kidney.
pelvis
The renal pelvis is the funnel-like structure at the center of the kidney.
What is Bowman’s capsule?
A structure in the nephron that encases the glomerulus
It is involved in the filtration of blood to form urine.
What is the function of the nephron?
The nephron is the functional unit of the kidney responsible for filtering blood and forming urine
Each kidney contains about a million nephrons.
What is the glomerulus?
A network of capillaries located within Bowman’s capsule
It plays a crucial role in the filtration of blood.
What is the role of the afferent arteriole?
It carries blood into the glomerulus
The afferent arteriole is responsible for supplying blood for filtration.
What does the efferent arteriole do?
It carries blood away from the glomerulus
This helps regulate blood flow and pressure within the nephron.
What is the descending limb of the loop of Henle?
The part of the loop of Henle that descends into the medulla
It is permeable to water but not to solutes.
What is the ascending limb of the loop of Henle?
The part of the loop of Henle that ascends back towards the cortex
It is impermeable to water and actively transports sodium and chloride ions.
What is the proximal tubule?
The segment of the nephron that reabsorbs most of the filtrate
It reabsorbs water, ions, and nutrients.
What is the distal tubule?
The segment of the nephron that further modifies the filtrate
It plays a role in the regulation of potassium, sodium, and pH.
What is the collecting duct?
The structure that collects urine from multiple nephrons
It is involved in the final concentration of urine.
What are the main components of filtrate?
H2O, Salts (NaCl, etc.), HCO3- (bicarbonate), Urea, Glucose, amino acids, Some drugs
Filtrate is the fluid that passes through the glomerular capsule and contains various substances that are reabsorbed or secreted in the nephron.
What is the process by which substances are moved from the blood into the filtrate?
Secretion (active transport)
Secretion is an important process in the kidneys that helps to eliminate waste products and maintain electrolyte balance.
Which part of the nephron is primarily responsible for reabsorption?
Proximal tubule
The proximal tubule reabsorbs a significant amount of water, glucose, amino acids, and electrolytes.
Fill in the blank: The _______ is responsible for the concentration of urine.
Loop of Henle
The Loop of Henle plays a critical role in creating a concentration gradient in the medulla, which is essential for water reabsorption.
What ions are primarily reabsorbed in the distal tubule?
NaCl, HCO3-
The distal tubule adjusts the composition of urine by reabsorbing sodium chloride and bicarbonate.
True or False: The collecting duct is involved in the secretion of H+ and K+.
True
The collecting duct fine-tunes the composition of urine and helps regulate acid-base balance.
What substances are primarily excreted in urine?
H2O, Urea, NaCl
Urine is composed of waste products filtered and processed by the kidneys, including excess water and salts.
What mechanism allows for the movement of water in the nephron?
Passive transport
Water follows osmotic gradients and is reabsorbed through passive transport mechanisms in various parts of the nephron.
What types of transport are involved in the reabsorption process?
Active transport, Passive transport
Both active and passive transport mechanisms are essential for the reabsorption of vital substances in the nephron.
Fill in the blank: The _______ collects urine before it moves to the renal pelvis.
Collecting duct
The collecting duct is the final segment of the nephron that collects urine from multiple nephrons.
What is the role of HCO3- in the nephron?
Buffering blood pH
Bicarbonate ions play a crucial role in maintaining the acid-base balance in the body.
What is water balance?
Water balance is achieved through:
* Regulation of fluid excretion
* Regulation of blood volume and pressure
* Thirst
* Water reabsorption in the GI tract
Water balance is crucial for maintaining homeostasis in the body.
Which factors are involved in achieving water balance?
Water balance is achieved through:
* Regulation of fluid excretion
* Regulation of blood volume and pressure
* Thirst
* Water reabsorption in the GI tract
Each factor plays a significant role in maintaining hydration and overall health.
What detects too little water in the blood?
Hypothalamus
What hormone does the pituitary gland release when there is too little water in the blood?
ADH
What is the effect of ADH on blood water levels?
Blood water level returns to normal
How do kidneys respond to maintain blood water levels?
Less water is lost in urine
What is the concentration of urine when the kidneys retain more water?
Urine is more concentrated
Fill in the blank: The _______ maintains blood water level.
[kidneys]
True or False: The hypothalamus is responsible for detecting too much water in the blood.
False
What happens when there is too much water in the blood?
Not specified in the text
What is another name for Antidiuretic hormone?
Vasopressin
What type of physiological effect does Antidiuretic hormone (ADH) have?
Vasoconstrictor
Is Antidiuretic hormone (ADH) more sensitive to blood volume or plasma osmolarity?
Plasma osmolarity
What triggers the release of Antidiuretic hormone (ADH)?
Large loss of blood
Name one factor that can trigger the release of Antidiuretic hormone (ADH).
Nausea
Name another factor that can trigger the release of Antidiuretic hormone (ADH).
Drugs
True or False: Antidiuretic hormone (ADH) is less sensitive to plasma osmolarity than blood volume.
False
What system regulates blood volume and pressure?
Renin-angiotensin system
The renin-angiotensin system is crucial for maintaining blood pressure and fluid balance.
What triggers the renin-angiotensin system?
Drop in blood pressure and drop in fluid volume
These drops signal the kidneys to release renin.
Where is angiotensinogen produced?
Liver
Angiotensinogen is the precursor to angiotensin I.
What enzyme is released from the lungs to convert angiotensin I?
ACE (angiotensin-converting enzyme)
ACE converts angiotensin I to angiotensin II.
What effect does angiotensin II have on blood vessels?
Stimulates vasoconstriction (narrowing)
This action increases blood pressure.
What does angiotensin II stimulate in the adrenal gland?
Release of aldosterone
Aldosterone plays a key role in sodium and water balance.
What does aldosterone do in the kidneys?
Stimulates reabsorption of salt (NaCl) and water (H2O)
This reabsorption helps to increase blood volume and pressure.
Fill in the blank: Renin acts on angiotensinogen to form _______.
angiotensin I
This is the first step in the renin-angiotensin system.
True or False: Angiotensin II decreases blood pressure.
False
Angiotensin II actually increases blood pressure through vasoconstriction.
What are the four major stimuli for thirst?
- Increased osmolarity of fluid surrounding osmoreceptors in hypothalamus
- Reduced blood volume and pressure
- Increased angiotensin 2
- Dryness of the mouth and mucous membranes lining the oesophagus
These stimuli trigger the thirst mechanism in the body, indicating a need for fluid intake.
What is the primary function of water reabsorption in the GI tract?
Manages many litres of fluid each day
Water reabsorption is crucial to prevent rapid dehydration.
What would happen if all fluids from the GI tract were excreted?
Would dehydrate rapidly
This highlights the importance of fluid balance in the body.
Which parts of the intestine are responsible for reabsorbing most of the water?
Small and large intestines
These structures play a key role in maintaining hydration.
What effect do excess water intake and diuretics have on antidiuretic hormone (ADH) secretion?
They decrease the secretion of antidiuretic hormone (ADH)
Diuretics include substances like alcohol and caffeine.
What happens to ADH levels when there is a fall in ADH?
The kidneys concentrate solutes in extracellular fluid by excreting water.
What are the two main actions of the kidneys in response to decreased ADH levels?
- Decrease permeability so collecting ducts and tubules retain water for excretion
- Excrete large volumes of dilute urine
True or False: Alcohol and caffeine increase the secretion of antidiuretic hormone (ADH).
False
Fill in the blank: A fall in ADH levels signals the kidney to _______.
[excrete water]
How do the kidneys correct the initial decreased concentration of solutes in extracellular fluid?
By concentrating solutes through water excretion.
What is a major killer worldwide?
Dehydration
Dehydration contributes significantly to mortality rates globally.
Which infections are linked to dehydration?
Gastrointestinal infections
These infections can exacerbate dehydration.
What physical condition increases the risk of dehydration?
Burns
Burns can lead to fluid loss and higher dehydration risk.
Which populations are more at risk for dehydration?
- Older adults
- Infants
These groups have a higher susceptibility to dehydration.
What is the first effect of progressive dehydration at 1% body weight loss?
Increased thirst, loss of appetite, discomfort
These are initial signs of dehydration.
What happens at 3% body weight loss due to dehydration?
Impatience, decreased blood volume
Decreased blood volume can affect overall health.
What are the effects of 4% body weight loss from dehydration?
Nausea, slowing of physical work
Physical performance begins to decline at this stage.
At what percentage of body weight loss does difficulty concentrating occur?
5%
Cognitive functions can be impaired by dehydration.
What symptoms are observed at 6% body weight loss?
Increasing body temperature, pulse and respiration rate
These are signs of severe dehydration.
What happens at 7% body weight loss due to dehydration?
Stumbling, headache
Neurological effects become prominent.
At 8% body weight loss, what symptoms are present?
Dizziness, labored breathing
Respiratory function may be compromised.
What is the consequence of 9% body weight loss from dehydration?
Weakness, mental confusion
Severe cognitive and physical impairment occurs.
What severe condition can occur at 10% body weight loss?
Muscle spasms, indistinct speech
This indicates critical dehydration and potential emergency.
What are the critical outcomes of 11% body weight loss due to dehydration?
Kidney failure, poor circulation due to decreased blood volume
These are life-threatening conditions.
What are the initial symptoms of water intoxication?
Headaches and confusion
Water intoxication occurs when there is an imbalance in the body’s electrolytes due to excessive water intake.
What severe conditions can water intoxication lead to?
Seizures and death
These severe outcomes are the result of disrupted electrolyte balance.
What typically causes water intoxication?
Rapid consumption of water
This often happens when replacing fluid losses with plain water during prolonged exercise.
What glandular disorders can lead to water intoxication?
Untreated glandular disorders
These disorders may affect the body’s ability to regulate water balance.
How common is water intoxication?
Rare
The kidneys can excrete many liters of fluid per day, making water intoxication uncommon.
What are minerals?
Inorganic elemental atoms or ions
Minerals are essential for various bodily functions and are not easily destroyed.
What is the daily intake requirement for major minerals?
> 100mg/day
Major minerals are required in larger quantities compared to trace minerals.
What is the daily intake requirement for trace minerals?
<100mg/day
Trace minerals are needed in smaller amounts but are still crucial for health.
What roles do minerals play in the body?
Essential roles in the body
Minerals are involved in a variety of functions including structural, regulatory, and metabolic processes.
What is the approximate amount of selected minerals in a 70 kg (154 lb) man?
1,200 grams
This amount varies based on individual dietary intake and physiological needs.
What are the two categories of minerals?
- Major minerals
- Trace minerals
These categories are based on the required daily intake amounts.
Fill in the blank: Major minerals are required in quantities greater than _______.
100mg/day
Fill in the blank: Trace minerals are required in quantities less than _______.
100mg/day
What are the primary electrolytes involved in fluid balance?
Sodium, calcium, potassium, chlorine, phosphate, and magnesium
These minerals play essential roles in maintaining various physiological functions.
What is one key function of electrolytes?
Maintain fluid balance
Electrolytes help regulate the amount of water in the body.
What is another important function of electrolytes?
Maintain blood pH
Electrolytes help to buffer acids and bases to keep blood pH within a narrow range.
What role do electrolytes play in the nervous system?
Maintain nerve transmission
Electrolytes are crucial for the generation and conduction of electrical impulses in nerves.
How do electrolytes affect muscle function?
They maintain muscle function
Electrolytes are essential for muscle contraction and relaxation.
What are the two primary sources of minerals in foods?
Both plants and animal sources
What does bioavailability refer to in the context of minerals?
Body adjusts mineral absorption to our needs
What is megadosing?
Taking excessively high doses of minerals
What is one factor that affects the bioavailability of minerals?
Person’s need
Fill in the blank: The _______ of the intestinal environment can affect mineral absorption.
Acidity
Name two substances that can affect mineral absorption.
- Phytate
- Oxalate
What are polyphenols in relation to mineral absorption?
Substances that can hinder mineral absorption
What can compete with minerals for absorption in the body?
Other minerals
What is sodium classified as?
Essential nutrient
What is the chemical formula for table salt?
NaCl
What is the major cation in extracellular fluid (ECF)?
Sodium
List three functions of sodium.
- Fluid balance
- Blood pressure
- Nerve impulse transmission
What is the recommended maximum intake of salt per day?
Not more than 6g (or 2.4g Na)
What types of foods are significant sources of sodium?
- Salt
- Processed foods
- Convenience foods
What is the recommended nutrient intake (RNI) of sodium for adults?
1600 mg/d
What is sodium classified as?
Essential nutrient
What is the chemical formula for table salt?
NaCl
What is the major cation in extracellular fluid (ECF)?
Sodium
List three functions of sodium.
- Fluid balance
- Blood pressure
- Nerve impulse transmission
What is the recommended maximum intake of salt per day?
Not more than 6g (or 2.4g Na)
What types of foods are significant sources of sodium?
- Salt
- Processed foods
- Convenience foods
What is the recommended nutrient intake (RNI) of sodium for adults?
1600 mg/d
What percentage of dietary sodium is added during food processing?
75%
This highlights the significant role of food processing in sodium intake.
What percentage of dietary sodium occurs naturally in food?
10%
This indicates that only a small portion of sodium is naturally present in foods.
What percentage of dietary sodium is used in cooking and at the table?
15%
This shows the contribution of cooking and table use to overall sodium intake.
What is hyponatremia?
Condition of low blood sodium concentrations
Hyponatremia can lead to serious health issues if not addressed properly.
What are the causes of hyponatremia?
- Severe diarrhoea
- Vomiting
- Intense prolonged sweating with replacement of water but not sodium
These causes lead to a significant loss of sodium in the body.
What symptoms are similar to dehydration in hyponatremia?
Symptoms similar to dehydration
Symptoms can include thirst, dry mouth, and fatigue.
What happens to cells in severe hyponatremia?
Extracellular fluid moves into cells, causing them to swell
This swelling can lead to seizures and coma if untreated.
What is the treatment for hyponatremia?
Replacement of minerals & fluid
This can be achieved through food and intravenous solutions.
What is hypernatremia?
High concentration of sodium in the blood
What can cause hypernatremia?
Rapid intake of large amount of sodium (e.g. drinking seawater)
What is a consequence of hypernatremia?
Hypervolemia - abnormal increase in blood volume
What are the symptoms of hypernatremia?
- Edema (swelling)
- Rising in BP
In which patients is hypernatremia usually seen?
- Patients with congestive heart failure
- Patients with kidney disease
What is hypertension?
Persistent high blood pressure
Hypertension is often a chronic condition that can lead to serious health issues.
What dietary factors are associated with hypertension?
- High intake of sodium
- High intakes of fat (especially saturated fat)
These dietary factors can contribute significantly to the development of hypertension.
What does DASH stand for?
Dietary Approaches to Stop Hypertension
The DASH diet is designed to help prevent and manage high blood pressure.
What are the key recommendations of the DASH studies for managing hypertension?
- Limit your sodium, fat, and cholesterol
- Increase fruit and vegetable intake
- Consume low-fat dairy foods
Following these recommendations has been shown to significantly lower blood pressure in hypertensive individuals.
What is the ideal blood pressure range?
Below 120/80 mmHg
Blood pressure is measured in millimeters of mercury (mmHg) with two numbers: systolic (top number) and diastolic (bottom number).
Fill in the blank: A high intake of _______ is associated with hypertension.
sodium
True or False: Increasing fruit and vegetable intake can help lower blood pressure.
True
What is a significant dietary change recommended for hypertensive individuals?
Increasing fruit and vegetable intake
This change is part of the DASH diet recommendations.
What is the key cation in intracellular fluid (ICF)?
Potassium
Potassium plays a crucial role in various physiological functions.
List three functions of potassium.
- Muscle contraction
- Nerve impulse transmission
- Regulates blood pressure
These functions are essential for maintaining overall health and bodily functions.
What is the recommended dietary intake (RNI) of potassium?
3500 kg/d
This recommendation may vary based on individual health needs.
Name three food sources of potassium.
- Unprocessed foods: fruits, vegetables, grains
- Meat
- Fish
These foods are generally rich in potassium.
What are some examples of less processed foods that contain potassium?
- Whole milk
- Roast beef
- Fresh corn
- Fresh cucumber
- Fresh peaches
- Wheat flour
These foods provide essential nutrients with lower levels of processing.
What are some examples of more processed foods that contain potassium?
- Chocolate pudding
- Corned beef
- Canned corn
- Dill pickle
- Canned peaches
- Whole wheat bread
While these foods provide potassium, they may also contain higher levels of sodium and preservatives.
What is the chemical symbol for Potassium?
K
What is the atomic weight of Potassium?
39.098
What is hypokalemia?
Low blood potassium
What is a likely risk factor associated with hypokalemia?
Hypertension risk
How can hypokalemia affect acid-base balance?
Can disrupt acid-base balance
Who is at risk for Potassium deficiency?
Individuals such as alcoholics, those with eating disorders, strong laxative use, diuretic hypertension medications
What are common symptoms of hypokalemia?
- Muscle weakness
- Loss of appetite
- Confusion
What is the atomic number of Potassium?
19
What is the atomic weight of Potassium?
39.098
What is Hyperkalemia?
High blood potassium
Is Hyperkalemia common or rare?
Rare
What can cause Hyperkalemia?
- Malfunctioning kidney
- Excess intravenous potassium
What can severe Hyperkalemia affect?
Can slow heart
What is hyperkalemia?
High blood potassium
Hyperkalemia is a condition characterized by elevated levels of potassium in the blood.
What are the common causes of hyperkalemia?
- Malfunctioning kidney
- Excess intravenous potassium
These factors can lead to an accumulation of potassium in the bloodstream, resulting in hyperkalemia.
What is a potential consequence of severe hyperkalemia?
It can slow heart
Severe hyperkalemia can lead to dangerous heart rhythms and may require immediate medical intervention.
Is hyperkalemia a common condition?
Rare
While hyperkalemia can occur, it is not frequently encountered in the general population.
What is the atomic symbol for potassium?
K
The letter ‘K’ is derived from the Latin word ‘kalium.’
What is the atomic mass of potassium?
39.098
This value represents the average atomic mass of potassium isotopes.
What is the daily value of potassium?
Daily Value = 3500 mg
Name three food sources of potassium that provide 20% DV or more.
- White beans
- Dates
- Raisins, seedless
What is a food source of potassium that is classified as ‘high’?
White beans
What are some examples of food sources of potassium that provide 10-19% DV?
- Potato, baked
- Yogurt, plain, nonfat
- Tomato juice
- Clams, cooked
- Halibut, cooked
- Banana
- Spinach, raw
- Orange juice, chilled
- Lima beans, cooked
- Milk, 1% milkfat
- Baked beans, canned
- Cantaloupe
- Acorn squash, cooked
- Apricot, fresh
Fill in the blank: A medium banana contains ______ mg of potassium.
487 mg
How much potassium is in 240 ml (1 cup) of tomato juice?
556 mg
True or False: Sweet potatoes are a food source of potassium.
True
What is the potassium content in 140 g (½ medium melon)?
374 mg
What is the potassium content in 85 g (3 oz) of spinach, raw?
474 mg
How much potassium is found in 225 g (1 8-oz container) of yogurt, plain, nonfat?
574 mg
List two food sources of potassium that are legumes.
- Lentils
- Baked beans, canned
What is chloride not the same as?
‘Chlorine’
Chloride is a distinct chemical ion, different from chlorine gas.
What is chloride’s role in the extracellular fluid (ECF)?
Major anion
Chloride is a key negatively charged ion in the extracellular fluid.
What is one of the functions of chloride in the body?
Moves in and out of red blood cells
This movement is essential for maintaining acid-base balance.
What is hydrochloric acid commonly known as?
Stomach acid
Hydrochloric acid is crucial for digestion in the stomach.
What is the dietary recommendation for chloride intake?
2500 mg/d
This recommendation supports various bodily functions.
Name a common food source of chloride.
Table salt
Table salt (sodium chloride) is the primary source of chloride in the diet.
What is hypochloremia?
Low chloride levels in the blood
Hypochloremia can lead to various health issues.
What condition can frequent vomiting lead to regarding chloride levels?
Hypochloremia
Conditions like bulimia nervosa can cause frequent vomiting, affecting chloride levels.
What metabolic condition is associated with hypochloremia?
Metabolic alkalosis
Metabolic alkalosis is characterized by elevated blood pH and bicarbonate levels.
What is the atomic number of Calcium?
20
What is the atomic weight of Calcium?
40.078
What role does Calcium play in the bone structure?
Bone matrix
List three functions of Calcium in the human body.
- Nerve function
- Blood clotting
- Muscle contraction
Calcium is important for _______ metabolism.
[cellular]
What percentage of calcium is found in bones and teeth?
99%
Calcium is crucial for bone structure and health.
What is the plasma calcium concentration range in mg/100ml?
9-10.4 mg/100ml
This concentration is vital for various physiological functions.
What are the two types of cells involved in bone remodeling?
- Osteoblasts
- Osteoclasts
Osteoblasts are responsible for bone formation, while osteoclasts are involved in bone resorption.
Why is adequate calcium intake necessary?
To maintain living tissue and bone structure
Insufficient calcium can lead to weakened bones and other health issues.
What process do osteoclasts perform?
Bone resorption
This process is essential for the maintenance and remodeling of bone.
What process do osteoblasts perform?
Bone formation
Osteoblasts help in building new bone tissue.
Fill in the blank: Calcium is essential for _______.
bone structure
Calcium is a critical mineral for maintaining bone integrity.
What is one of the primary functions of calcium in the body?
Nerve function
Calcium is essential for the normal transmission of nerve impulses.
How does calcium contribute to muscle contraction?
Flow of calcium inside muscle cells allows them to contract and relax
Calcium facilitates the interaction of myosin and actin for muscle contraction.
What triggers the release of neurotransmitters?
Calcium
Calcium plays a crucial role in the process of neurotransmitter release in nerve function.
Fill in the blank: Calcium facilitates the interaction of _______ and actin.
myosin
Myosin and actin are proteins that interact during muscle contraction.
True or False: Calcium is not involved in nerve function.
False
Calcium is essential for the normal transmission of nerve impulses.
What are the functions of calcium in the body?
- Blood clotting
- Cellular metabolism
What is the role of calcium in blood clotting?
- Formation of fibrin
- Blood-clotting cascade
- Blood will not clot in the absence of calcium
How does calcium contribute to cellular metabolism?
- Binds to and activates calmodulin
- Cell secretions
- Cell division
- Cell proliferation
What is the dietary recommendation for calcium intake?
700 mg/d
This is the general recommendation for daily calcium intake for adults.
Name three food sources of calcium.
- Milk and dairy products
- Green vegetables
- Tofu
- Fortified foods
These foods are rich in calcium and contribute to meeting dietary recommendations.
What is hypocalcemia?
Low levels of calcium in the blood
Hypocalcemia can lead to various health issues, including muscle spasms and seizures.
What is hypercalcemia?
High levels of calcium in the blood
Hypercalcemia can cause symptoms such as fatigue, nausea, and confusion.
What condition is characterized by weak and brittle bones due to low calcium?
Osteoporosis
Osteoporosis increases the risk of fractures and is often related to inadequate calcium intake.
Fill in the blank: The recommended dietary intake for calcium is _______.
700 mg/d
This recommendation is crucial for maintaining bone health.
List two potential health issues related to calcium imbalance.
- Hypocalcemia
- Hypercalcemia
Both conditions can have significant health impacts and require management.
True or False: Tofu is a good source of calcium.
True
Tofu, especially when fortified, is an excellent plant-based source of calcium.
Name one vegetable that is a source of calcium.
Green vegetables
Examples include kale and broccoli, which provide calcium along with other nutrients.
What is the Daily Value of calcium?
1,000 mg
What qualifies as a high source of calcium?
20% DV or more
What qualifies as a good source of calcium?
10-19% DV
List three high-calcium foods.
- Tofu, calcium processed
- Yogurt, plain, lowfat
- Milk, nonfat
True or False: Spinach is a good source of calcium.
False
Fill in the blank: In spinach, oxalate binds calcium and prevents absorption of all but about ______ percent of the plant’s calcium.
5
List two vegetables that are good sources of calcium.
- Collards, cooked
- Turnip greens, cooked
What is the atomic number of Phosphorus?
30.974
What are the functions of Phosphorus?
- Bone structure
- Enzymes - phosphorylation
- Component of ATP, DNA, RNA, phospholipids
What is the dietary recommendation for Phosphorus intake?
550 mg/d
What are some food sources of Phosphorus?
- Meat
- Milk
- Eggs
- Processed foods
What condition is characterized by low levels of Phosphorus?
Hypophosphatemia
What condition is characterized by high levels of Phosphorus?
Hyperphosphatemia
What is the Daily Value (DV) for phosphorus?
1,000 mg
The Daily Value is a reference amount used for nutrition labeling.
What food sources of phosphorus are considered high in phosphorus content?
- Cheese, provolone
- Beef liver, cooked
- Yogurt, plain, nonfat
- Sunflower seeds
- Herring, cooked
- Milk, nonfat
- Milk, 1% milkfat
- Milk, 2% milkfat
- Chicken, white meat, cooked
- Beef, ground, extra lean, cooked
- Oysters, cooked
- Lentils, cooked
- Tofu, calcium processed
- Chicken, dark meat, cooked
- All Bran cereal
- Almonds
- Soy milk
- Black beans, cooked
- Peanut butter
Foods providing 20% DV or more are classified as high in phosphorus.
True or False: Lentils are a good source of phosphorus.
True
Lentils provide a significant amount of phosphorus.
List three food sources that provide a good amount of phosphorus (10-19% DV).
- Chicken, dark meat, cooked
- Soy milk
- Peanut butter
Foods providing 10-19% DV are classified as good sources of phosphorus.
What is the atomic symbol for Magnesium?
Mg
What is the atomic weight of Magnesium?
24.305
List three functions of Magnesium.
- DNA and protein synthesis
- ATP production
- Blood clotting, muscle contraction
What is the dietary recommendation for Magnesium intake?
300 mg/d
Name four food sources rich in Magnesium.
- Whole grains
- Vegetables
- Legumes
- Tofu
- Seafood
What condition is characterized by low levels of Magnesium?
Hypomagnesemia
What condition is characterized by high levels of Magnesium?
Hypermagnesemia
What is sulfur a component of?
Organic compounds
Sulfur is essential in forming various organic molecules.
What role does sulfur play in protein structure?
Forms disulfide bridges between amino acids
These bridges are critical for the stability and function of proteins.
What function does sulfur serve in the liver?
Drug-detoxifying pathways
Sulfur contributes to the metabolic processes that detoxify harmful substances.
Is sulfur deficiency common?
Unknown
There is plenty of sulfur supplied from protein consumption, making deficiency rare.
How is sulfur primarily obtained in the diet?
From protein consumption
Foods rich in protein provide adequate sulfur for bodily functions.