E4: Drug Abuse/Addiction Part III Opioids Flashcards

1
Q

What is the opioid WIDELY used by dentists?

A

OxyCodone

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2
Q

What is the legitamet medical use?

A

painkillers

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3
Q

Opioids are abused because they produce complete _______ of all drives in the body: Elevate mood, Cause euphoria.. Reduce sexual desires…Diminished response to provocation

A

satiation

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4
Q

Opiods: ________ dependency increases motivation to obtain the drug, because its mainly fear of _______ overriding motivation to stop

A

Physical…withdrawal

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5
Q

INTERESTING! ________ was designed for morphine tolerant patients?

A

Oxycodone

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6
Q

Oxy is “_______” – which dissolve slowly for extended release

A

layered

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7
Q

Which opioid is a RED FLAG request?

A

Roxicet (easier to dissolve, less binder)

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8
Q

What are the two main ingredients in Percocet and Roxicet?

A

Oxy + aCETaminophen…GET IT?!

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9
Q

In general _______-release, oral-dosage forms of opiates are highly monitored c/o abuse.

A

extended.. (they have much more drug in them!!)

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10
Q

SAY WHAT _______ deaths are now second only to major vehicle fatalities for number of deaths per year.

A

drug-induced

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11
Q

Number of _____ dying from opioid painkiller overdose has increased fivefold between 1999 to 2010

A

WOMEN

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12
Q

6600 women (18 women per day) died from prescription painkiller overdose in 2010….More than ________ and ______ combined

A

cocaine and heroin

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13
Q

What age range is most hit by this women and pain killers phenomenon?

A

25-54

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14
Q

Abuse of prescription painkillers by pregnant women can put an infant at risk….its called ______ and it grew by _____% from 2000 to 2009!

A

Neonatal Abstinence Syndrome…300%

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15
Q

The 5 CDC Opioid recommendations: 1. Follow guidelines for responsible opioid prescribing: _______ for substance abuse and mental health problems

A

screening

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16
Q

The 5 CDC Opioid recommendations: 2. Use ____’s prescription drug monitoring programs

A

State’s

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17
Q

The 5 CDC Opioid recommendations: Discuss pain treatment options, including :

A

those that DO NOT INVOLVE prescription drugs

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18
Q

The 5 CDC Opioid recommendations: Discuss risks/benefits of taking prescription painkillers like: _________ and ______

A

Chronic conditions and during pregnancy

19
Q

The 5 CDC Opioid recommendations: AVOID prescribing combinations of prescription painkillers and ________!!

A

benzodiazepines!!

20
Q

Clinicians must avoid ________ and limit quantities of prescribed pain medications and other controlled substances in an effort to help combat intentional drug abuse.

A

overprescribing

21
Q

What is the most RAPIDLY acing opiate?

A

heroin

22
Q

3 out of 4 NEW heroin users report having abused _______ prior to using heroin

A

prescription opioids

23
Q

Know These What are the 7 signs of ACUTE OPIOID OVERDOSE??

A

PCDS-SDH 1.pinpoint pupils 2.depressed respiration 3.Hypotension 4.Shock 5.Slow/Absent Reflexes 6.Drowsiness 7.Coma

24
Q

What are the two drugs used to treat overdose/withdrawal?

A

1.Naloxone(Narcan) and 2.Methadone

25
Q

Which drug am I? Used to reverse respiratory depression, pinpoint pupils and coma…Oral surgeons have this drug in office emergency kits….Used for acute narcotic overdose

A

Naloxone

26
Q

Which drug am I? Long-acting opioid that can replace heroin then be gradually withdrawn….Physiologically equivalent drug to heroin that is used during long-term rehabilitation programs

A

METH-A-DONE with heroine…(i think Tanner is on this one.)

27
Q

Watch for ____________: patients asking for very potent pain meds following dental procedures = a sign of addiction…..use ______ instead

A

drug-seeking behaviors (you know, you fit the MODEL for drug seeking behavior). use NSAIDS

28
Q

What are the 3 main consequences of using IV when abusing opioids?

A

1.Hep B 2.HIV 3.Damaged heart valves (antibiotic PREmed)

29
Q

T/F: Dentists prescribe prophylactic antibiotics to patients with a history of abusing IV drugs.

A

True

30
Q

What are 4 popular Benzo’s?

A

1.Diazepam (Valium) 2.Lorazepam(Ativan) 3.Triazolam (Halcion) 4.Midazolam(Versed)

31
Q

Which benzo I used as a sedative/ hypnotic sleeping pill?

A

Triazolam (Halcion)

32
Q

Which Benzo is used for pre-op sedation and for the induction of general anesthesia?

A

Mid-az-o-lam (Versed)

33
Q

Prescribers rarely understand addictive quality of Benzo’s with related complications in _____ patients

A

elderly

34
Q

Patients develop “____________” due to unavailability of benzo’s or during hospitalization for other medical problem

A

benzo-abstinence syndrome

35
Q

What are the 3 main indications for Benzodiazapines?

A

1.Chronic Anxiety 2.Depression 3.Sleep Disturbance (4.undercover staties’)

36
Q

If you suspect some one has chronic anxiety, you shold automatically check for _________

A

DEPRESSION

37
Q

Why aren’t Benzo’s a very good way to improve sleep disturbances?

A

Nightly use loses effectiveness in 3-6 months c/o tolerance

38
Q

Benzo’s: Significant ______ effect with other sedative hypnotic drugs (opiates, alcohol)

A

additive (TAG TEAM)

39
Q

Why do Benzo’s cause EASY intoxication?

A

They have a PROLONGED HALF LIFE!

40
Q

WE ALL KNOW that Benzo’s and EtOH DO NOT MIX. Why?

A

CNS depression–>RESPIRATORY depression-STOP breathing

41
Q

How long does the risk for mixing EtOH and benzo’s last, even after your last dose of Benzo?

A

Valium lasts 20-50 hours in its half life…SO DAYS after last dose!!

42
Q

What is the ANTIDOTE for BDZ Overdose? How does it work?

A

FLUM-AZ-EN-IL..its a BDZ antagonist (blocker)

43
Q

Why can FlumAZenil not reliably reverse the respiratory depression associated with BZD overdose?

A

It does not block the respiratory effects of the other combination drugs that caused an OD

44
Q

BDZ reversal may cause _______ = be prepared to manage

A

seizures