E1: CrossOver Heart Drugs

Question 1

What 4 drugs so far have drug interactions with NSAIDS?

Answer 1

Diuretics, Beta Blockers, Ace Inhibitors & Angiotensin Recteptor Blockers (ARBs)

Question 2

RED FLAG INTERACTIONS-what are the two antibiotics and what are the two heart drugs that contraindicate them??

Answer 2

1.Macrolides + 2.Antifungals DO NOT PLAY WELL WITH 1.HMG-CoA reductase inhibitors (statins for high cholesterol) & 2. Digoxin (for CHF & Arrythmia)

Question 3

**NSAIDS decrease the effectiveness of which 3 antiHTN meds??????

Answer 3

1.Beta Blockers 2.ACE inhibitors 3.Diuretics (thiazides & others)

Question 4

What are the 3 ANTIDOTES we learned??

Answer 4

1.Digoxin- Digibind 2.Heparin-Pro-tam-ine 3.tPA-Amicar

Question 5

What is a NOTORIOUS inducer of warfarin metabolism?

Answer 5

Phenytoin

Question 6

SIGNIFicant Dental Drug Interaction with Warfarin!!! _______ (_______) and warfarin (Coumadin) causes enhanced _________

Answer 6

acetaminophen (Tylenol)…. anticoagulation