E2: Ch 6 Flashcards
__ ___: form direct cytoplasmic connections between adjacent cells
Gap junctions
__-___ __: require interaction between membrane molecules on two cells
contact-dependent signals
__ ___: act on the same cell that secreted them. ___ ___: are secreted by one cell and diffuse to adjacent cells.
Autocrine signals, paracrine signals.
__: secreted by endocrine glands/cells into the blood.
hormone
___: chemicals secreted by neurons that diffuse across a small gap to the target cell.
neurotransmitters
____: chemical released by neurons into the blood for action at distant targets
neurohormones
__ molecule binds to __ protein that activates ___ signal molecules that alter __ proteins to create a ___
signal, receptor, intracellular, target, response
__ signal molecules diffuse through cell membrane and bind to cytosolic/ nuclear receptors
lipoPHILIC
__ signal molecules bind to receptors on surface of cell membrane
lipophobic
signal __ converts one form of signal into a different form
transduction
ligand binding to a ligand-gated channel ___/___ the channel
opens/closes
ligand binding to a receptor-enzyme activates an ___ enzyme
intracellular
ligand binding to a G-protein coupled receptor opens an __ channel or alters __ activity
ion, enzyme
ligand binding to integral receptors alters the ___
cytoskeleton
receptor-ligand complex activates an __ enzyme
amplifier
integrin involvement in platelet activation works by causing a __ change
shape