Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

T7. Pharmacology > Drugs_anti HIV > Flashcards

Drugs_anti HIV Flashcards

0
Q

Lamivudine

A

Antiviral drug_HIV

Nucleosides (NRTIs)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q

Zidovudin

A

Antiviral drug_HIV

Neucleosides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Zidovudine + Lamivudine (Combivir)

A

given after accidental needle stick

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Efavirenz

A

Antiviral drug_HIV

Nonnucleosides (NNRTIs)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Atazanavir

A

Antiviral drug_HIV

Protease inhibitor prevent formation of new viral particles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Fosamprenavir

A

Antiviral drug_HIV

Protease inhibitor; prodrug of amprevavir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Enfuvirtide

A

Antiviral drug_HIV

Fusion inhibitor block the binding of HIV to CD4 lymphocytes receptors that is required for HIV to enter cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Raltegravir

A

Antiviral drug_HIV

Integrase inhibitor prevent integration of viral DNA into the DNA of the infected cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

2 RT inhibitor + 1 protease inhibitor

A

most effective tx of HIV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Amantadine

A

Antiviral_Influenza

Influenza type A infection prevention and treatment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Zanamivir

A

Antiviral drug_Neuraminidase inhibitors

Influenza A and B infection prevention and treatment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Acyclovir

A

Antiviral_Herpes
Herpes simplex type 1 and 2 (HSV-1, HSV-2)
Varicella zoster virus (VZV)
Epstein-Barr virus (EBV), Cytomegalovirus (CMV)- mono
*TOPICAL, IV, ORALLY for herpes infections

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Foscarnet

A

Antiviral_herpes

approved for CMV retinitis, acyclovir-resistant HSV and VZV infections

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Gancyclovir

A

Antiviral_herpes

Drug of choice for Cytomegalovirus infections

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Aedefovir

A

Antiviral_hepatic viral

Hep B virus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Tenofovir

A

Antiviral_hepatic viral

Hep B virus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Pegylated interferon

A

Antiviral_hepatic viral
Hep B virus
inhibit viral RNA translation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Lamivudine

A

Antiviral_hepatic viral
Hep B virus
inhibitor of HBV DNA polymerase and HIV reverse transcriptase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Pegylated interferon alpha-2a

A

Antiviral_hepatic viral

Hep C infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Pegylated interferon alpha-2b

A

Antiviral_hepatic viral

Hep C infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Ribavirin

A

Antiviral_hepatic viral

Hep C infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Cyclophosphamide

A

Anticancer drug
Alkylating agent
Most commonly used alkylating agent

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

u/e Cyclophosphamide

A

hemorrhagic cystitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

6-mercaptopurine

A

Anticancer drug

Antimetabolites

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
5-flurouracil
Anticancer | Antimetabolites
25
Methotrexate
Anticancer drug Antimetabolites Psoriasis, severe active rheumatoid arthritis in addition to whole variety of cancers *administered intrathecally
26
Doxorubicin
Anticancer drug | Antibiotics
27
u/e Doxorubicin
Cardiotoxicity, alopecia and bone marrow depression
28
Bleomycin
Anticancer drug | Antibiotics
29
u/e Bleomycin
fatal pulmonary fibrosis | *extreme caution- preexisting history of lung disease
30
Plicamycin
Anticancer drug Antibiotics tx. Life-threatening hypercalcemia associated with malignancy
31
Vincristine
Anticancer drug | Microtubule inhibitor
32
u/e Vincristine
neurologic toxicity
33
Vinblastine
Anticancer drug | Microtubule inhibitor
34
u/e Vinblastine
bone marrow toxicity
35
Anastrozole
Anticancer drug Hormonal agent_aromatase inhibitor tx. estrogen-dependent breast cancer resistant to tamoxifen
36
Tamoxifen
Anticancer drug_Antiestrogen tx. estrogen receptor positive breast cancer * competitive antagonists of estrogen receptor
37
Flutamide
Anticancer drug_androgen receptor antagonist | tx. prostate cancer
38
Leuprolide
Anticancer drug_GnRh analog | tx. metastatic prostatic cancer
39
Rituximab
Anticancer drug_monoclonal antibodies | tx. chronic lymphocytic leukemia
40
Imatinib
Anticancer drug_other | tx. chronic myeloid leukemia
41
Geftinib
Anticancer drug_other | tx. non small cell lung cancer
42
Etoposide
Anticancer drug_other | tx. small cell carcinoma of the lungs
43
Cisplatin and Cardbaplatin
Anticancer drug_other | tx. testicular carcinoma, ovarian carcinoma, bladder carcinoma
44
Procarbazine
Anticancer drug_other | tx. Hodgkin's disease
45
L-asperginase
Anticancer drug_other | tx. childhood acute lymphocytic leukemia (ALL)
46
Bacille Calmette-Guerin (BGC) vaccine
TB vaccine, effective in treating small localized superficial urinary bladder carcinoma Intravesicular use Non-specific stimulant of the reticuloendothelial system
47
Asprin
Anti-inflammatory drug | Non selective inhibitors of cyclooxygenase
48
u/e Asprin
Reye syndrome if given in viral infections, especially in children
49
Diclofenac
Anti inflammatory drug | Non-selective inhibitors of cyclooxygenase
50
Indomethacin
Anti inflammatory drug Non selective inhibitors of cyclooxygenase tx. in patent ductus arteriosus (PDA) in new born babies
51
Celocoxib (Celebrax)
Anti inflammatory drug_selective COX-2 inhibitor | lower risk for GI bleeding, good for chronic use
52
u/e Celocoxib (Celebrex)
hypertention
53
Rofecoxib (Vioxx)
Anti inflammatory drug_selective COX-2 inhibitor | Withdrawn?
54
Acetaminophen
Anti inflammatory drug_analgesics | antipyretic, analgesic; weak anti inflammatory activity
55
Infliximab
Anti inflammatory drug_arthritis | Crohn's disease
56
Methotrexate
Anti inflammatory drug_disease-modifying anti-rheumatic drug
57
D-Penicillamine
Anti inflammatory drug_disease-modifying anti-rheumatic drug | also tx. heavy metal poisoning, Wilson's disease
58
Aliopurinol
Gout | reduce uric acid formation
59
Colchicine
Gout drug | tx. acute attack of gout
60
Probenecid
Gout drug | uricosuric drug- increase uric acid excretion by the KD
61
Cyclosprorine (CsA)
Immunosuppressive drug_selective inhibitors of cytokine production and fx Prevention and treatment of transplanted organ rejections
62
u/e Cyclosprorine (CsA)
nephrotoxicity, thromboembolism, neurotoxicity, seizure etc.
63
Azathioprine
Immunosuppressive drug_immunosuppressive antimetabolites | t-cells and b-cells are particularly affected by the inhibition of purine synthesis
64
Mycophenolate mofetil
Immunosuppressive drug_immunosuppressive antimetabolites | inhibits an enzyme that helps the growth of Tcells and Bcells

T7. Pharmacology (16 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions