Drugs Affecting Blood

Question 0

How does tranexamic acid work?

Answer 0

Reduces activation of plasminogen

Question 1

Name two anticoagulants

Answer 1

Heparin and warfarin

Question 2

Name and anti-fibrinolytic drug

Answer 2

Tranexamic acid

Question 3

How does heparin work?

Answer 3

Activates anti thrombin, inactivates thrombin and Xa

Question 4

How does dipyridamole prevent thrombus formation?

Answer 4

Increases Camp levels, clot can’t form

Question 6

Name a fibrinolytic drug

Answer 6

Alteplase

Question 7

How does warfarin work?

Answer 7

Vitamin k antagonist, stops clotting factors becoming activated

Question 8

What drugs affect thrombus formation?

Answer 8

Aspirin, Clopidogrel, Epoprostenol, Dipyridamole

Question 9

How does aspirin prevent thrombus formation?

Answer 9

By blocking COX enzyme, prevents TxA2 synthesis

Question 10

How does alteplase work?

Answer 10

Converts plasminogen to plasmin, plasmin dissolves fibrin

Question 12

How does clopidogrel prevent thrombus formation?

Answer 12

Blocks activation of glycoprotein llb/llla

Question 13

How does epoprostenol prevent thrombus formation?

Answer 13

Increases Camp levels