Applied Pharm - Hypoglycaemics

Question 1

Name 3 short acting insulins

Answer 1

Aspart
Glulisine
Lispro

Question 2

Name an intermediate acting insulin

Answer 2

Isophane insulin

Question 3

Name 4 long lasting insulins

Answer 3

Protamine zinc insulin
INsulin zinc suspension
Insulin detemir
Insulin glargine

Question 4

What is a healthy fasting blood sugar?

Answer 4

3-5 mmol/L

Question 5

What is healthy blood sugar after a meal?

Answer 5

7-10mmol/L

Question 6

Where are the main targets for insulin?

Answer 6

Muscle, fat and liver

Question 7

What is a biphasic preparation?

Answer 7

Mixture of intermediate and short duration insulins

Question 8

When is glucagon therapy used?

Answer 8

For severe hypoglycaemia

Question 9

What do secratogues I do?

Answer 9

Boost insulin release

Question 10

Name 4 short acting Secratogues 1?

Answer 10

Glicazide, Tolbutamide, Repaglinide, Nateglinide

Question 11

Name 3 long acting Secratogues I drugs

Answer 11

Chlorapropamide, Glibenclamide, Glucatrol

Question 12

Name 2 Secratogues II drugs

Answer 12

Incretin mimetic

Byetta

Question 13

Name a drug used in hyperglycaemia

Answer 13

Diazoxide

Question 14

How do biguanides work?

Answer 14

Prevent hepatic glucose production

INcreases insulin sensitivity

Question 15

MOst common biguanide?

Answer 15

Metformin

Question 16

Name 5 combo therapies for T2DM

Answer 16

Pioglitazone
Glipizide
Glibenclamide
Sitagliptin
Repaglinide

Question 17

What do thiazolidinediones target?

Answer 17

Adipocytes

Question 18

Name a thiazolidinedione

Answer 18

Rosiglitizone

Question 19

How does acarbose work?

Answer 19

Prevents sugar spikes by slowing starch absorption

Question 20

What do SGLT2 inhibitors do?

Answer 20

Cause excess glucose to be excreted

Question 21

Name 3 SGLT2 inhibitors

Answer 21

Dapagliflozin
Canagliflozin
Empagliflozin