DRUGS Flashcards
What is Tolerance?
- Requires more drug to produce same effect
OR - Decreased sensitivity to a drug with same dose
Dependence:
Occurs when a drug becomes so incorporated into the functioning of the body’s cells that it becomes necessary for “normal” functioning
Craving:
Strong desire to engage in behavior or consume a substance
Withdrawal:
Compensatory action of the nervous system that looks like the opposite action of a dru
What is Addiction?
A chronic, relapsing brain disease that is characterized by compulsive drug seeking and use, despite harmful consequences.
Dependence on a drug such that stopping its use results in withdrawal symptoms
Drugs change the brain’s structure and how it works
Why do people take drugs?
- 4.
Feel good/Mimic natural highs Feel better
Perform better Curiosity/Perceived norm
- 4.
Development of Drug Abuse
Initial + effects of drug use
Pleasurable activities become less pleasurable Drug use becomes necessary to feel “normal” Continued seeking/use of drug despite problems
Initial decision: voluntary
Continued use: when drug use takes over, ability to exert self-control may become impaired
Areas most effected by drug use:
Brain stem Limbic system Cerebral cortex
Frontal cortex/forebr
Drugs and the Brain
Drugs tap into brain’s communication system and interfere with the way nerve cells normally send, receive, and process information
Marijuana and heroin: Chemical structures mimic normal neurotransmitters
Amphetamine and cocaine: Cause nerve cells to release abnormally large amounts
Dopamine & Drugs
regulates movement, emotion, cognition, motivation, feelings of pleasure
• Some drugs can release 2-10 times the amount of dopamine that natural rewards do (eating and sex)
• Immediate effects (smoking, injection) and longer lasting effects
• Powerful rewards motivate people to take drugs again and again
• Abusers need to take drugs to try and bring dopamine functions back to normal
• Tolerance = needed to take larger amounts of drug
Serotonin:
regulates mood and sleep
Glutamate:
regulates learning and memory
Medical Consequences:
Cardiovascular disease • Stroke • Cancer • HIV/AIDS • Hepatitis B and C • Lung disease • Mental Disorders • Negative effects of prenatal drug use on infants and children
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Mental Health Consequences:
Depression
Anxiety
Bipolar disorder
ADHD (attention-deficit/hyperactivity disorder) Antisocial personality disorder
Overlapping genetic vulnerabilities Overlapping environmental triggers Involvement of similar brain regions
Treatment and Recovery
like other chronic diseases Relapse rates = how often symptoms recur Both biological and behavioral components must be addressed Abstinence and restored functioning is often a long- term process Treatment and Recovery • • • • Support group participation