Drugs

Question 1

Alpha-2

Answer 1

Presynaptic, feedback inhibitor

• inhibits gut Ach (decreases motility)
• decreases insulin secretion from pancreas
• agonist: xylazine, detmodine
• antagonist: yohimbine, atipamezole

Question 2

Beta-1

Answer 2

Excitatory, heart

• positive inotrope and chronotrope
• increased blood pressure via increased in renin secretion from juxtoglomerular cells, conserve Na and water
• agonist: iso > epi and norepi
• Antagonist: propranolol

Question 3

Beta-2

Answer 3

Inhibitory, relaxes smooth muscle, bronchioles

• bronchodilation
• relaxation of smoth msucle
• vasodilation to abdominal viscera, kidneys, lungs and skeletal muscle
• increased secretions
• gluconeogenesis in liver

Question 4

Alpha-1

Answer 4

Post-synaptic, excitatory, smooth muscle and glands

• increases constriction and excretion
• vasoconstriction
• agonist: epi > norepi
• antagonist: prazosin