DPC Respiratory Flashcards
Albuterol
ProAir HFA, Proventil HFA, Ventolin HFA
B2 selective agonist
MDI, Powder for inhalation, DPI, tablet, ER tablet, syrup, solution
Asthma (acute, bronchospasm, exercise induced)
Azelastine
Astelin, Astepro
nasal antihistamine–H1 receptor antagonist blocks release of histamine (inhibits leukotrienes)
Perennial allergic rhinitis, Seasonal allergic rhinitis, vasomotor rhinitis
Benzonatate
Tessalon Perles
antitussive–anesthetizing the stretch receptors located in respiratory passages, lungs, pleura
Capsule, 100-200mg TID prn
Cough
Budesonide
Pulmicort
inhaled corticosteroid–potent glucocorticoid and weak mineralocorticoid activity
Inhalation suspension, MDI
Asthma 180-360mcg BID
Budesonide/Formoterol
Symbicort Inhaled corticosteroid/bronchodilator--potent glucocorticoid and weak mineralocorticoid, formoterol long acting selective B2 agonist produces bronchodilation MDI Asthma 80/4.5mcg 2 inhalations BID COPD 160/4.5mcg 2 inhalations BID
Fluticasone (nasal inhaler)
Flonase Intranasal adrenal glucocorticosteroid--induction of phospholipase A2 inhibitory proteins, lipocortins nasal spray Allergic rhinitis 2 sprays daily Nonallergic rhinitis 2 sprays/nostril/d
Fluticasone (oral inhaler)
Flovent HFA, Flovent Diskus
Inhaled Adrenal corticosteroid–glucorticoid receptor agonist inhibits multiple cell types
MDI, Aerosol powder for inhalation
Asthma 88mcg BID (max 440mcg BID)
Fluticasone/Salmeterol
Advair Diskus, Advair HFA
Inhaled corticosteroid–glucocortioid receptor agonist that inhibits multiple cells types, Salmeterol is long acting B2 agonist stimulates intracellular adenylyl cyclase (ATP)
Hydroxyzine
Atarax, Vistaril Antihistamine--rapid acting agent suppressing locations in CNS subcortical area (primary skeletal muscle relaxation, bronchodilator activity, antiemetic Tablet, Capsule, syrup, solution Anxiety 50-100mg QID Pruritus 25mg TID-QID Sedation 50-100mg q4h
Ipratroprium/Albuterol
Combivent Respimat
Anticholinergic/Selective B2 agonist–bronchodilation, vasodilation, uterine relaxation, skeletal muscle stimulation, peripheral vasodilation, tachycardia, Ipratropium antagonist of Ach in peripheral
Inhalation solution, spray for oral inhalation
COPD 1 inhalation QID
Levalbuterol
Xopenex HFA
B2 selective agonist, bronchodilator–B2 on airway smooth muscle which activates cAMP
MDI, nebulization solution
Asthma, bronchospasm 2 inhalations q4-6h
Levocetirizine
Xyzal
antihistamine–low-sedating, long acting H1 receptor antagonist
solution, tablet
Idiopathic urticaria, perennial, seasonal allergic rhinitis 5mg daily in evening
Mometasone (nasal)
Nasonex
Intranasal corticosteroid–induction of phospholipase A2 inhibitor proteins, lipcortins
nasal spray
Seasonal and perennial allergic rhinitis 2 sprays/nostril/d 200mcg
Nasal polyp 2 sprays/nostril BID
Montelukast
Singulair
leukotriene receptor antagonist–inhibits physiologic actions of leukotriene
tablet, chewable tablet, granules
Asthma 10mg daily
Exercise induced asthma 10mg 2h before exercise
Seasonal allergic rhinitis 10mg daily
Tiotropium
Spiriva Handihaler, Respimat Anticholinergic bronchodilator--M1-M5 receptor--inhibition of M3 at the smooth muscle leading to bronchodilation Inhalation capsule, aerosol solution COPD 1 capsule daily, 2actuations daily Asthma 2 actuations daily
