Antidepressants Flashcards

1
Q

Mixed 5HT/NE reuptake inhibitor

A

TCA
Venlafaxine
Desvenlafaxine
Duloxetine

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2
Q

Venlafaxine

A

Effexor

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3
Q

Venlafaxine SE

A

Agitation, HA, insomnia, sexual dysfunction, increase diastolic BP**

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4
Q

Desvenlafaxine

A

Pristiq

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5
Q

Duloxetine

A

Cymbalta

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6
Q

Duloxetine AE

A

CNS (sedation, dizziness, HA, insomnia)
GI (N/V/D)
Xerostomia
**changes in BP (caution with uncontrolled HTN)

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7
Q

SSRIs

A
Fluoxetine
Paroxetine 
Sertraline 
Fluvoxamine
Citalopram 
Escitalopram
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8
Q

Fluoxetine

A

Prozac

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9
Q

Paroxetine

A

Paxil

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10
Q

Sertraline

A

Zoloft

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11
Q

SSRI SE

A

Nausea, insomnia, HA, weight neutral
Sedation, sexual dysfunction
Initial increase in anxiety

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12
Q

Paxil SE

A

Anticholinergic

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13
Q

Zoloft SE

A

GI (diarrhea and loose stools)

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14
Q

Mixed serotonin effects

A

Trazodone

Nefazodone

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15
Q

Trazodone

A

Desyrel

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16
Q

Nefazadone

A

Serzone

17
Q

Nefazodone SE

A

Sedation, orthostasis, dry mouth, nausea

Black Box: **liver failure

18
Q

Nefazadone benefits

A

Less sexual dysfunction, agitation, and weight changes

19
Q

Mixed NE/DA reuptake inhibitor

A

Bupropion

20
Q

Bupropion SE

A

Agitation, nausea, HA, seizures, tremor, insomnia

21
Q

Bupropion benefits

A

Less sexual dysfunction

Less likely to induce mania

22
Q

Bupropion disadvantages

A

Higher seizure potential

AVOID in pets with pre-existing seizures, bulimia, anorexia, alcohol withdrawal

23
Q

Mixed 5HT/NE effects

A

Mirtazapine

24
Q

Mirtazapine

A

Remeron

25
Q

Mirtazapine SE

A

Sedation (doses <15mg)
Increase appetite, weight gain
Increase total cholesterol, TG, glucose dysregulation
Dry mouth, constipation, orthostasis

26
Q

MAOI

A

Phenelzine
Tranylcypromine
Selegiline

27
Q

MAOI SE

A

DDI/DFI: hypertensive crisis—stroke

Selegiline transdermal is less

28
Q

TCA SE

A

Anticholinergic, antihistamine, hypotension, sedation, tachycardia, weight gain, sexual dysfunction, decrease seizure threshold

29
Q

TCAs

A
Amitriptyline 
Amoxapine 
Desipramine
Doxepin 
Imipramine
Nortriptyline 
Protriptyline
Trimipramine
30
Q

Serotonin syndrome

A

GI symptoms, tremors, hyperreflexia, restlessness, tachycardia, HTN, manic-like symptoms, confusion, hyperpyrexia

31
Q

Discontinuation syndrome

A

Vivid dreams, nightmares, tremor, dizziness, crying spells, nausea, poor concentration