Diseases of the nervous system Flashcards
2 branches of the nervous system
central nervous system and peripheral nervous system (CNS and PNS)
2 branches of PNS
autonomic nervous system (heart muscle, smooth muscle, glands) and somatic nervous system (skeletal muscles)
2 branches of autonomic nervous system
parasympathetic (rest and digest) and sympathetic (fight or flight)
parts of CNS
brain and spinal cord
diseases of the brain
trauma, seizures, and neoplasia
etiology of trauma
literally anything, very common in vet med
clinical signs of trauma
aural, oral, oculonasal hemorrhaging, seizures, abnormal behavior, shock, cardiac arrhythmias, altered RR
Dx trauma
clinical signs, Hx, CT, MRI
Tx trauma
varies, supportive care, control seizures, monitor O2 levels, steroids
Px trauma
varies on severity
What does trauma do to the brain
increased intracranial pressure (ICP)
the brain in encased in ____ and there is no room for ____
bone; swelling
meds for seizures
diazepam, propofol, phenobarbital
acute disorder of middle aged dogs and cats
idiopathic vestibular diseasec
clinical signs of vestibular disease
loss of balance, nystagmus, disorientation, ataxia, vomiting, anorexia
Dx vestibular disease
clinical signs, rule out inner ear infection, metabolic disorder, infectious or inflammatory response, neoplasia
Tx for vestibular disease
Cerenia for motion sickness, supportive
recurrent seizures with no demonstrated cause
Idiopathic seizures
breed disposition for seizures
GSD, poodle, cocker spaniels, beagles, goldens, irish setters
seizures begin around what age?
1-3 years
clinical signs leading up to seizures
pre-ictal phase
period after seizure where animal is still disoriented/obtunded
post-ictal phase
cause of seizures
extracranial and intracranial
Tx for seizures
try to find underlying cause and control the clinical signs
Dx for seizures
CBC, UA, MRI
seizures must be distinguished from____
syncope (falling asleep)
seizure lasting for over 5 minutes
status epilepticus
why are prolonged seizures a true emergency?
can lead to coma and death
Tx for epilepticus
diazepam, phenobarbital IV, established airway, monitor, supportive care
etiology of neoplasia
unknown
signalment for neoplasia
older patients
clinical signs for neoplasia
altered mentation, seizures, head tilt, vestibular disease, ataxia
Dx for neoplasia
advanced imaging
Tx for neoplasia
chemo is an option, mostly supportive
disease of cartilage formation of middle aged chondrodystrophic animals
intervertebral disc disease (IDD)
breed disposition of IDD
dachshund, bulldog, corgi, pug, french bulldog, basset hound, Pekinese, beagle, poodle
what is IDD
herniation of intervertebral disc into spinal cord causing inflammation of the spinal cord
clinical signs of IDD
acute pain, tense abdomen, hunched appearance, paresis or paralysis, proprioceptive deficit, +/- deep pain, +/- incontinence
Dx IDD
Hx, clinical signs, imaging
Tx of IDD
medically or surgically, nursing care
IDD grade 5
normal
IDD grade 4
cervical or thoracolumbar pain
IDD grade 3
paresis, decreased proprioception, ambulatory
IDD grade 2
severe paresis, absent proprioception, not ambulatory,
IDD grade 1
paralysis, no bladder control
IDD grade 0
paralysis, incontinence, no pain perception
prognosis for IDD
grade 2,3, and 4 good prognosis
grade 1 and 0 is not very good
condition where dens is malformed or missing
Atlantoaxial subluxation (AA lux)
wobblers disease
cervical spondylomyelopathy
etiology of cervical spondylomyelopathy
malformation or misarticulation of caudal cervical vertebrae
what is wobblers disease?
compression of spinal cord which causes a wobbly gait, neurological signs, and neck pain
signalment for wobblers
large/giant dog breeds, horses 4-18 months
clinical signs for wobblers
wobbly gait mostly in back end, 5% of wobblers cases are paralyzed in all 4 limbs
Dx for wobblers
radiographs, MRI, myelogram in horses
Tx for wobblers
medical management, limiting movement, Sx
prognosis of wobblers
50% of dogs improve, 30% remain the same, and 20% worsen
chronic, progressive disease of spinal cord and brainstem which results in paralysis and death
degenerative myelopathy
etiology of degenerative myelopathy
degeneration of white matter in spinal cord, a gene is associated with this disease
signalment for degenerative myelopathy
GSD and mixes
clinical signs of degenerative myelopathy
hindlimb paresis, ataxia, muscle atrophy, non painful
Dx of degenerative myelopathy
CSF tap
Tx degenerative myelopathy
supportive
etiology of discospondylitis
infectious agents become implanted into bones of vertebral column
bacteria causing discospondylitis
Brucella canis, Staph, E. coli, Aspergillus
clinical signs of discospondylitis
fever, depression, pain, neurologic sign
Dx discospondylitis
rads, urine and blood cultures, B canis slide agglutination
Tx discospondylitis
antibiotics
etiology of fibrocartilaginous embolism
ischemia of spinal cord from obstructed veins and arteries
clinical signs of fibrocartilaginous embolism
paresis or paralysis of limbs with no pain
signalment of fibrocartilaginous embolism
large breeds 1-9 yo
Dx fibrocartilaginous embolism
diagnosis of exclusion
Tx fibrocartilaginous embolism
steroids, supportive care
conductive deafness
secondary to severe otitis, rupture of tympanic membrane, damage to middle ear
neural deafness
may be hereditary, congenital, secondary to drug toxicity
clinical signs of deafness
no response to stimuli, sleeping
Tx for deafness
none
client education for deafness
special needs, specific training methods
metabolic neuropathy
hyperthyroidism, Diabetes mellitus, hyperadrenocorticism
Dx metabolic neuropathy
bloodwork
Tx for metabolic neuropathy
correct underlying disease
clinical signs of metabolic neuropathy
muscle weakness, muscle atrophy, paresis, paralysis
lar par
laryngeal paralysis
lar par can be
hereditary or acquired
clinical signs of lar par
resp distress, +/- collapse or cyanosis
Dx of lar par
endoscopy, exam
Tx lar par
tie back Sx
megaesophagus
esophagus becomes dilated
etiology of megaesophagus
hereditary or acquired (Addisons, tick paralysis, distemper, lead poisoning)
clinical signs of megaesophagus
regurgitation of undigested food, resp signs
Dx of megaesophagus
rads
Tx of megaesophagus
elevated food platform, small meals, manage aspiration pneumonia
tick paralysis
you already know
etiology of coonhound paralysis
thought to be from racoon saliva or bite
clinical signs of coonhound paralysis
after racoon bite, weakness in back legs and eventually front legs
Dx coonhound paralysis
Hx of racoon bites, rads
Tx coonhound paralysis
supportive