Disease Classifications Flashcards
Diseases that are present at birth and result from genetic or environmental factors
Congenital Disease
Caused by developmental disorders genetically transmitted from either parent to child through abnormalities of individual genes in chromosomes and derived from ancestors
Hereditary Diseases
A congenital condition caused by an autosomal mitosis error, leading to an extra twenty first chromosome so that the affected individual has 47 chromosomes rather than the normal 46
Down syndrome
A well-known hereditary disease in which proper blood clotting is absent
Hemophilia
A genetic abnormality present on the sex chromosome
Sex-linked inheritance
A genetic abnormality present on one of the other 22 chromosomes
Autosomal inheritance
transmitted by a single gene from either parent
Dominant
transmitted by both parents to an offspring
Recessive
One of the most common chromosomal variations in humans. Patients with this syndrome have atleast one extra X chromosome
Klinefelter’s syndrome
Characteristics of Klinefelter’s syndrome
- enlarged breast (gynecomastia)
- sparse facial and body hair
- small testes
- inability to produce sperm (azoospermia)
Characteristics of Turner’s syndrome
- webbing at the back of their necks
- underdevelopment sex organs
- absence of menstruation (amenorrhea)
- puffiness of hands and feet
- occasionally dwarfism
a rare condition that left the newborn limbless except for a right foot and two toes
Tetra Amelia Syndrome
Examples of dominant gene disorders
Achondroplasia
Polydactyly (extract digit)
A hollow needle is inserted through the mother’s abdomen into the uterus, and amniotic fluid is drawn for analysis
Amniocentesis
results from the body’s reaction to localized injurious agent
Inflammatory Disease
result from invasion by microorganisms such as viruses, bacteria, or fungi
Infective diseases
result from poisoning by biologic substances
Toxic diseases
an overreaction of the body’s own defense
Allergic disease
diseases associated with autoantibodies
Autoimmune Disorders
Ex of Autoimmune Disorders
Rheumatoid arthritis
antibodies form against and injure the patient’s own tissues
Autoantibodies
A generalized pathologic process that is nonspecific to the agent causing the injury
Inflammatory reaction or inflammation