Digestive System Flashcards

1
Q

Intracellular digestion

A

Occurs within the cell, often membrane bound vesicles

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2
Q

Extracellular digestion

A

Occurs outside of the cell, within lumen/tract

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3
Q

Outline the pathway of food starting from oral cavity.

A

Oral cavity –> Pharynx –> Esophagus –> Stomach –> Small intestine –> Large intestine – Anus

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4
Q

What type of digestion occurs in the mouth?

A

-Mechanical (mastication) and chemical (salivary amylase)

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5
Q

Salivary amylase

A

-Breaks starch into maltose (disacc)

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6
Q

Peristalsis

A
  • Rhythmic waves of involuntary muscular contractions

- Esophagus

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7
Q

What separate the stomach and esophagus?

A

-Lower esophageal (cardiac) sphincter

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8
Q

Compare the relative pressure of the thoracic and abdominal cavities

A
  • Thoracic cavity (where body of esophagus is) negatively pressured relative to environment on inhalation
  • Abdominal cavity (+) pressure
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9
Q

Gastroesphageal reflux disease (GERD)

A
  • Results from pressure gradients

- Reflux of gastric material into esophagus

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10
Q

What are chief cells?

A
  • In gastric glands

- Produce pepsinogen

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11
Q

What are parietal cells?

A
  • In gastric glands

- Synthesize/release HCl and intrinsic factor (absorb vitamin B12)

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12
Q

What is the role of HCl?

A
  • Converts pepsinogen to pepsin

- Kills bacteria

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13
Q

What kind of digestion is in stomach?

A

-Mechanical (churning) and Chemical

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14
Q

Where does chyme pass into?

A

-Duodenum through pyloric sphincter

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15
Q

What lines the stomach walls?

A

-Gastric mucosa secreted by mucous cells

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16
Q

Where does chemical digestion finish?

A

-Small intestine

17
Q

What are the sections of the small intestine?

A

-Duodenum, Jejunum, Ileum

18
Q

What do villi consist of?

A

-Capillaries and lacteals

19
Q

Where do large fatty acids and glycerol go from the small intestine?

A

-Pass to lacteals then moved to liver where they’re converted to tryglycerides

20
Q

Which nutrients are actively absorbed?

A

-Amino acids and glucose

21
Q

Where does most digestion in small intestines occur?

22
Q

What does intestinal mucosa secrete?

A
  • Lipases
  • Aminopeptidases
  • Disaccharidases
23
Q

Where and what is the function of gastrin?

A
  • Produced by G cells in duodenum
  • Stimulate histamine and pepsinogen secretion
  • Stimulate parietal cells
24
Q

Where and what is the function of intrinsic?

A
  • Secreted by parietal cells

- Facilitate absorption of vitamin B12

25
Cholecystokinin (CCK)
- Produced by I cells of duodenal/jejunal mucosa - Stimulate panreatic snzyme and somatostatin secretion - Stimulate gallbladder contraction - Hunger suppressant
26
Secretin
- Synthesized by S cells of upper intestine - Stimulate secretion of bicarbonate-containing substances from pancreas - Inhibit gastric emptying and gastric acid production
27
Bile
- Produced by liver and stored in gallbladder | - Release to small intestine to emulsify fats
28
What is the purpose of emulsifying fats?
-Increase surface area for lipases
29
What are functions of the liver?
- Store glycogen - Convert ammonia to urea - Protein synthesis - Detoxification - Cholesterol metabolism
30
What does the pancreas produce?
- Amylase, trypsin, lipase | - Secrete bicarbonate containing substances
31
Large intestine
-Absorb salt and any water not absorbed by small intestine
32
Rectum
-Transient storage of feces --> anus