Development L6 - Palate Flashcards
the palatal shelves meet at the midline to form the what?
medial edge epithelium, which bond to form the medial edge epithelium seam.
palatal shelve elevation is said to be a result of intrinsic and extrinsic force, which force involves the tongue.
extrinsic forces
describe what happens during week 8 in reference to the tongue
continued foetal development of the oro-naso cavity results in the withdrawl of tongue inferiorly
osteoblasts that trapped in the bone are called what
osteocytes
formation of the MME seam triggers a series of biochemical and cellular reactions causing what
degeneration of the MEE seam
the formation of the palate occurs during which weeks
male: 6-12 weeks
female 7-12 weeks
]. The contact of the palatal shelves initiates adhesion between the two MEE layers, forming the?
MME seam
the development of the palate occurs at which cavity
oro-naso cavity
during weeks 7-8 intramembranous ossfication occurs, what do mesenchymal cells differentiate to facilitate intramembranous ossification
mesenchmyal cells differentiate to osetoblasts
what irole does the secondary palate have
separates the nasal airway and the oral cavity
important for:
mastication - bolus formation
sensation - tase and texture
speech
what three factors result in the withdrawl of the tongue
head lifting from cardiac plate
meckels cartilage growth
increase in height of nasal cavity
what do osteblasts deposit to produce bone
osteoid
the primary palate is derived from what?
fused nasal prominences with inter-maxillary segment
what stage in devlopment is the foetus (weeks)
and which three features are being developed
foetus is at 6 weeks in development
during the 6th week the following is developed
- development of the palatal shelves
- development of the tongue, which moves superiorly
- development of the nasal septum
what would you expect to see in reference to the palatal shelves during week 7
continued growth of palatal shelves.
the palatal shelves would be vertically orientated due to the large tongue
the downward movement of the tongue allows teh palatal shelves to do what?
the palatal shelves flip in a horizontal position.
what are the three palatal fusion theories out there
EMT = epithelial - mesenchymal transition
palatal shelve elevation is said to be a result of intrinsic and extrinsic factors, which force is generated within the palate
intrinsic forces
what occurs during week7-8 in the primary palate
intramembranous ossification occurs at the ossification centres around the perpendicular plate.
hyaluronan acts as a intrinsic factor, what role does hyaluronan have in palatal shelve elevation
hyaluronan accumulates prior to elevation, it brings in water and allows for the hydration of the extracellular matrix,. the pressure of the water helps push the palatal shelves in to a horizontal position.
whcich signalling protein results in the formation of filopodia
TGFβ3
what would you expect to see during week 7 in reference to the tongue
the continued growth of the tongue sees that it occupies a large proportion of the oro-nasal cavity.
the primary palate sets the boundaries between which components
oral and nasal components
