Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Hematology 1 [LEC] > Description of Red Blood Cell (RBC) Abnormalities and Commonly Associated Disease States > Flashcards

Description of Red Blood Cell (RBC) Abnormalities and Commonly Associated Disease States Flashcards

1
Q

Abnormal variation in RBC volume or diameter

A

Anisocytosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Large RBC (.8 mm in diameter), MCV .100 fL

A

Macrocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Large oval RBC

A

Oval macrocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Small RBC (,6 mm in diameter), MCV ,80 fL

A

Microcyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Abnormal variation in RBC shape

A

Poikilocytosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Small, round, dense RBC with no central pallor

A

Spherocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Elliptical (cigar-shaped)

A

Elliptocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

oval (egg-shaped), RBC

A

ovalocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

RBC with slit-like area of central pallor

A

Stomatocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Thin, dense, elongated RBC pointed at each end; may be curved

A

Sickle cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Hexagonal crystal of dense hemoglobin formed within the RBC membrane

A

Hb C crystal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Fingerlike or quartz-like crystal of dense hemoglobin protruding from the RBC membrane

A

Hb SC crystal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

RBC with hemoglobin concentrated in the center and around the periphery

A

Target cell (codocyte)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Fragmented RBC due to rupture in the peripheral circulation

A

Schistocyte (schizocyte)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

RBC fragment in shape of a helmet

A

(keratocyte)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

RBC with membrane folded over

A

Folded cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Small, dense RBC with few irregularly spaced projections of varying length

A

Acanthocyte (spur cell)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

RBC with blunt or pointed, short projections that are usually evenly spaced over the surface of cell; present in all fields of blood film but in variable numbers per field

A

(echinocyte)
Burr cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

RBC with a single pointed extension resembling a teardrop or pear

A

Teardrop cell (dacryocyte)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Hemolytic anemia

A

Anisocytosis
Diffuse basophilia
Howell-Jolly body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Immune hemolytic anemia

A

Spherocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Microangiopathic hemolytic anemia

A

Schistocyte (schizocyte)
microspherocytes
Helmet cell (keratocyte)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Extensive burns

A

Spherocyte
Schistocyte (schizocyte)
microspherocytes
Helmet cell (keratocyte)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Macroangiopathic hemolytic anemia

traumatic cardiac hemolysis

A

Schistocyte (schizocyte)
Helmet cell (keratocyte)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Megaloblastic anemia

A

Anisocytosis
Macrocyte
Oval macrocyte
Teardrop cell (dacryocyte)

Basophilic stippling
Howell-Jolly body
Pappenheimer bodies
Cabot ring

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Iron deficiency anemia

A

Anisocytosis
Microcyte
Elliptocyte, ovalocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Myelodysplastic syndrome

A

Macrocyte
Basophilic stippling
Howell-Jolly body
Pappenheimer bodies
Cabot ring

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Primary myelofibrosis

A

Teardrop cell (dacryocyte)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Myelophthisic anemia

A

Teardrop cell (dacryocyte)
Elliptocyte, ovalocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Chronic liver disease

A

Macrocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

liver disease, alcoholism

A

Stomatocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

Liver disease only

A

Target cell (codocyte)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

Severe liver disease (spur cell anemia)

A

Acanthocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

Hyposplenism

A

Howell-Jolly body
Pappenheimer bodies*

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

Postsplenectomy

A

Howell-Jolly body
Pappenheimer bodies*

36
Q

Bone marrow failure

A

Macrocyte

37
Q

Reticulocytosis

A

Macrocyte

38
Q

Anemia of chronic inflammation

A

Microcyte

39
Q

Sideroblastic anemia

A

Microcyte
Pappenheimer bodies*

40
Q

Severe anemia; certain shapes helpful diagnostically

A

Poikilocytosis

41
Q

Sickle cell anemia

A

Sickle cell

42
Q

Sickle cell–b-thalassemia

A

Sickle cell

43
Q

Thalassemia

A

Microcyte
Target cell (codocyte)
Teardrop cell (dacryocyte)
Basophilic stippling
Howell-Jolly body
Pappenheimer bodies*

44
Q

Thalassemia major

A

Elliptocyte, ovalocyte

45
Q

Hb E disease

A

Microcyte

46
Q

Hb C disease

A

Hb C crystal
Folded cell

47
Q

Hb SC disease

A

Hb SC crystal
Folded cell

48
Q

Hemoglobinopathies

A

Target cell (codocyte)
Basophilic stippling
Pappenheimer bodies**

49
Q

Unstable hemoglobins

A

Heinz body

50
Q

Hb H disease

A

Hb H

51
Q

Hereditary

A

Spherocyte
Elliptocyte, ovalocyte
Stomatocyte

52
Q

Rh deficiency syndrome

A

Stomatocyte

53
Q

Artifact

A

Stomatocyte

54
Q

Neuroacanthocytosis

A

Acanthocyte (spur cell)

55
Q

abetalipoproteinemia

A

Acanthocyte (spur cell)

56
Q

McLeod syndrome

A

Acanthocyte (spur cell)

57
Q

Uremia

A

Burr cell (echinocyte)

58
Q

Pyruvate kinase deficiency

A

Burr cell (echinocyte)

59
Q

After treatment for iron, vitamin B12, or folate deficiency

A

Diffuse basophilia

60
Q

Lead poisoning

A

Basophilic stippling

61
Q

Glucose-6-phosphate dehydrogenase deficiency

A

Heinz body

62
Q

Oxidant drugs/chemicals

A

Heinz body

63
Q

Stain dark blue and are called siderotic granules when observed in Prussian blue stain

A

Pappenheimer bodies

64
Q

†Cells with similar morphology that are unevenly distributed in a blood film (not present in all fields) are likely due to a drying artifact in blood film preparation; these artifacts are sometimes called crenated RBCs

A

Burr cell (echinocyte)

65
Q

**new methylene blue

A

Supravital Stain

66
Q

***Stain dark blue and are called siderotic granules when observed in Prussian blue stain.

A
67
Q

Appearance in Supravital Stain: Dark blue granules and f ilaments in cytoplasm (seen in reticulocytes)

A

Diffuse basophilia

68
Q

Appearance in Supravital Stain and Wright’s stain: Dark blue-purple, fine or coarse punctate granules distributed throughout cytoplasm

A

Basophilic stippling

69
Q

Appearance in Supravital Stain and Wright’s stain: Dark blue-purple dense, round granule; usually one per cell; occasionally multiple

A

Howell-Jolly body

70
Q

Appearance in Supravital Stain: Round, dark blue-purple granule attached to inner RBC membrane

A

Heinz body

71
Q

Appearance in Supravital Stain: Irregular clusters of small, light to dark blue granules, often near periphery of cell

A

Pappenheimer bodies

72
Q

Appearance in Supravital Stain: Rings or figure-eights

A

Cabot ring

73
Q

Appearance in Supravital Stain: Fine, evenly dispersed, dark blue granules; imparts “golf ball” appearance to RBCs

A

Hb H

74
Q

Appearance in Wright Stain: Bluish tinge throughout cytoplasm; also called polychromasia (seen in polychromatic erythrocytes)

A

Diffuse basophilia

75
Q

Appearance in Wright Stain: Not visible

A

Heinz body
Hb H

76
Q

Appearance in Wright Stain: Irregular clusters of small, light to dark blue granules, often near periphery of cell

A

Pappenheimer bodies

77
Q

Appearance in Wright Stain: Blue rings or figure-eights

A

Cabot ring

78
Q

Inclusion Composed of: RNA

A

Diffuse basophilia

79
Q

Inclusion Composed of: Precipitated RNA

A

Basophilic stippling

80
Q

Inclusion Composed of: DNA (nuclear fragment)

A

Howell-Jolly body

81
Q

Inclusion Composed of: Denatured hemoglobin

A

Heinz body

82
Q

Inclusion Composed of: Iron

A

Pappenheimer bodies

83
Q

Inclusion Composed of: Remnant of mitotic spindle

A

Cabot ring

84
Q

Inclusion Composed of: Precipitate of b-globin chains of hemoglobin

A

Hb H

85
Q

thrombotic thrombocytopenic purpura

A

Schistocyte (schizocyte)
microspherocytes
Helmet cell (keratocyte)

86
Q

‘hemolytic uremic syndrome

A

Schistocyte (schizocyte)
microspherocytes
Helmet cell (keratocyte)

87
Q

disseminated intravascular coagulation

A

Schistocyte (schizocyte)
microspherocytes
Helmet cell (keratocyte)

Hematology 1 [LEC] (25 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions