Dermatology Flashcards
What is eczema?
Itchy dry inflammatory skin disease
What are flares of eczema in childhood associated wth?
Infection/vital illness Central heating, cold hair Pets Teething Stress
What are the endogenous types of eczema?
Atopic Seborrhoeic Discoid Pomphylx Varicose
What causes atopic eczema?
Genetic and immune mediated barrier dysfunction
What is atopy?
Tendency to eczema, asthma and hayfever
What is the pathology of atopic eczema?
Abnormality in flaggrin expression- flaggrin proteins bind keratin filaments together
Loss of water, irritant and allergens can penetrate
What is the presentation of atopic eczema in infancy?
Typically starts on face and neck, cheek most common
Can spread ore generally
What is th presentation of atopic eczema in older children?
Flexural pattern predominates
Facial eczema can recur
What is the presentation of seborrhoeic eczema?
Mainly face and scalp, scaly appearance
In babies under 3 months, usually resolves by 12 months
What is seborrhoeic eczema associated with?
Proliferation of various species of skin commensals in yeast form
What is the treatment of seborrhoeic eczema?
Emollients
Antifungal creams and shampoos
Mild topical steroids
What is the presentation of discoid eczema?
Scattered annular/circular patches of itchy eczema
Can occur in pattern as a part of atopic eczema or separate entity
Who is pomphylx eczema seen in?
Young females
What is the presentation pf pomphylx eczema?
Vesicles affecting palms and or soles
Can be intensely itchy
What is varicose eczema?
Dry, inflamed possibly ulcerated skin caused by venous insufficiency
What is the treatment of varicose eczema?
Emollients
Topical steroids
Compression stockings
What are the exogenous causes of eczema?
Allergic
Irritant
What is allergic eczema?
Sensitisation to allergen causes eczema
What are the most common allergies?
Milk/dairy Soy Peanuts Eggs Wheat Fish
What causes irritant eczema?
Repeated contact with irritant
What is the treatment of eczema?
Emollients Topical steroids Calcineurin inhibitor UVB light therapy Immunosuppression
What are the possible side effects of topical steroids?
Skin thinning with prolonged use