Dementia Flashcards
What are the features of Alzheimers?
memory loss particularly short term; dysphasia; dyspraxia and agnosia
What may be seen on CT/MRI with alzhemeirs?
medial temporal lobe atrophy or temperoparietal atrophy
What symptoms are more common in vascular dementia than alzhemiers?
dysphasia; dysclaculia; frontal lobe symptsom and affective symptoms
What are the additional features of vascular dementia?
focal neuro signs; vascular risk factors ; step wise decline
What may be seen on CT/MRI in vascualr dementia?
mod-severe small vessel disease or multiple lacunar infarcts
What amy be seen onsSPECT with vascualr demetnia?
patchy reduction in tracer uptake thorught the brain?
What are the three syndrome in frontotemporal dementia?
behavioural variant; praimry progressive aphasia; semantic dementia
What are the features of beahvioural variant of frontotemproal dementia?
behavioursal changes, executive dysfunction; disinihibtion; impulsivitiy; loss ofo social skills; apathy; obsessions; change in diet
What are hte features of primary progessive aphasia?
effortful non-fluent speech; speech sound/articulatory errors; lack of grammar; lack of words
What are the features of semantic dementia?
impaired understanding of meaning of works; fluent but empty speech and difficulty retrieiving names
What are the common early features of lewy body dementia?
reduced attention; executive function; visuospatial skiills
What are the features of dementia with Lewy Body?
visual hallucitnation;s fluctuaing cognition (delirium-like); REM sleep behviour disorder; Parkinsonsism; positive DAT scan
How many people with Parkinsons develop dementia?
80% after 15-20 years of PD
What cholinesterase inhibitors are used in Alzheimers?
donepezil; rivastigmine; galantamine
What cholinesterase inhibitor can be used in Lewy Body and PD
rivastigmine
