Deep Brain Stimulation Flashcards
1
Q
DBS Procedure
A
Stimulating electrodes are placed stereotactically into certain deep brain structures
Secured to skull + into ear down neck
3-4 years battery replacement
2
Q
DBS treating Parkinson’s
A
Only the motor systems
Not non-motor - gait, balance, cognitive problems, depression
3
Q
Criteria DBS Parkinson’s
A
Idiopathic PD No sensory issues- numbness etc No weakness or hyperreflexia No mental disorders Still respond to Levodopa
4
Q
Zona Incerta
A
Tremor
5
Q
Subthalamic nucleus
A
tremor
6
Q
Globus pallidus internus
A
Dystonia and tremor
7
Q
Other brain regions DBS
A
Epilepsy- only reduce doesn’t eliminate seizure frequency
Chronic neuropathic pain -reduces does not eliminate
8
Q
Tourette syndrome
A
Thalamic centromedian
9
Q
Treatment resistant depression
A
Brodmann area 25 (subcallosal cingulate)
10
Q
Anorexia
A
Hypothalamus
11
Q
Addiction
A
Nucleus accumbens
12
Q
Alzheimers disease
A
Anterior of fornix
13
Q
Mechanisms of DBS
A
4 Hypotheses: Inhibition Excitation Disruption Neuro-network modulation
