deck 34 Flashcards
initial therapy for atrial fibrillation due to hyperthyroidism
beta-blockers
potassium in patients with hyperosmolar hyperglycemic state
1) pts have a total body potassium deficit (glucose induces osmotic diuresis which sucks potassium out) (same is true for DKA)
2) problem with this is that insulin can abruptly lower serum potassium levels and cause severe hypokalemia
common cause of hypocalcemia in alcoholics
hypomagnesemia (causes decreased release of PTH and PTH resistance).
other impt cause of hypercalcemia
prolonged immobilization (due to increased osteoclastic activity)
treatment of hypercalcemia 2/2 immobilization
bisphosphonates
problem with pulse ox for CO poisoning
may appear normal because it can’t differentiate carboxyhemoglobin from oxyhemoglobin
exam finding suggesting CO poisoning
bright cherry lips
thyroid tumor and elevated calcitonin?
medullary thyroid cancer
next step after medullary thyroid cancer is diagnosed
screen for pheochromocytoma prior to thyroidectomy with plasma fractionated metanephrine assay
diabetes and polyneuropathy pathophys
- microvascular injury + demyelination + oxidative stress + deposition of glycosylation end products
- this leads to a length-dependent axonopathy
- clinical features depend on the type of nerve fibers involved
- small fiber injury is characterized by positive symptoms (pain, paresthesias, allodynia)
- large fiber involvement is characterized by predominance of negative symptoms (numbness, loss of proprioception and vibration sense, diminished ankle reflexes)
primary hyperaldosteronism lab profile
HTN + mild hypernatremia + metabolic alkalosis + suppressed plasma renin (this is because of feedback inhibition in response to aldosterone secreting tumor)
management of caustic ingestion with sodium or potassium hydroxide (lye)
endoscopy to assess severity of damage
arsenic sources
pressure-treated wood + pesticides
arsenic poisoning presentation
painful sensorimotor polyneuropathy + hypo and hyper pigmented skin lesions + pancytopenia + mild transaminase elevation
patient populations with atypical ACS symptoms
women + elderly + diabetics
common atypical ACS presentations
dyspnea + epigastric pain + N/V
type 1 MEN
primary hyperparathyroidism + pituitary tumors + GI/pancreatic endocrine tumors
thyroid storm presentation
tachycardia + HTN + arrhythmias + high fever +tremor + AMS + lid lag
hypothermia management
mild with passive rewarming, severe with active rewarming (heated blankets) + heated peritoneal irrigation (internal warming)
methanol intoxication
vision loss + coma