Day 8 - cardiac diseases Flashcards

1
Q

General steps of exam of cardiac diseases

A
  • Detailed physical examination at rest
  • Exercise test/performance analysis (is the cardiac problem the cause?, subclinical and transient problems)
  • Echocardiography: murmurs, pericardial effusion
  • ECG: arrythmias (exercise test)
  • Laboratory parameters (hematology, biochemistry, microbiology, cytology (pericardial effusion))
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Left-sided congestive heart failure (CHF)

A

acute: lung-edema,
chronic: cardiac cachexia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Right-sided heart failure:

A

ventral oedema, venous pulsation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

consequence of unilateral HF

A

will become bilateral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Most common congestive HF

A

Valvular heart disease (+ atrial fibrillation)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

CS of HF

A

Exercise intolerance
Slow return to resting values
Weight loss
Cough
Tachycardia
Tachypnoea
Ventral edema
Pulmonary congestion, edema
Colic-like signs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

CHF - Tx (4)

A
  • Digoxin
  • Furosemide
  • Potassium chloride
  • ACE inhibitors
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Congenital diseases

A
  • Ventricular septal defect, atrial septal defect
  • Abnormal valves
  • Complex cardiac defects
  • Vascular malformations (Patent ductus arteriosus)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Vascular septal defect - Tx

A
  • Most common, Inherited
  • Basal area
  • Signs depend on size: > 2,5 cm: Left to right shunt
  • Cardiac murmur: Holo- or pansystolic, grade 3-5/6, point of maximum intensity (PMI) below tricuspid opening
  • Dx: 2D and Doppler echocardiography
  • Tx: as CHF or euthanasia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Ventricular septal defect - Eisenmengers syndrome

A

right to left shunt

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Acquired heart diseases - Endocardium and valves

A

Bacterial/vegetative endocarditis (infective)
Degenerative thickening of the valves
Valvular dysfunction, secondary to myocardial disease Ruptured chordae tendinea
Prolapse of valves
Aortic regurgitation
Mitral regurgitation
Tricuspid regurgitation
Pulmonary regurgitation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Acquired heart diseases - Myocardium

A
  • Myocarditis (equine influenza, herpesvirus, rhinopneumonitis, bacterial)
  • Myocardial fibrosis (Ischemic or strongylosis)
  • Myocardial degeneration/necrosis (Toxic or Se/Vit E def.)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Acquired heart diseases - Neoplasia and Dilated cardiomyopathy

A

Lymphosarcoma, melanoma, haemangio(sarco)ma

(idiopathic) - rarely

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Acquired heart diseases - Arrhytmias

A
  • Atrial, junctional and ventricular premature complexes
  • Atrial tachycardia, flutter, fibrillation
  • Ventricular tachycardia, flutter, fibrillation
  • Second and third degree atrioventricular blocks: 1st degree always physiological
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Grade 5 L-sided murmur (holosystolic)

A

mitral regurgitation/aortic stenosis –> a. stenosis Ø common in adult horses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Grade 5 L-sided murmur (holodiastolic)

A

Ø have to think about mitral stenosis

17
Q

Bacterial endocarditis - Pathogens and CS

A

o Streptococcus Equii ssp equi, Streptococcus Equi ssp zooepidemicus, Actinobacillus equuli, Rhodococcus equi

  • Mitral, aortic, tricuspid, pulmonary (high to low)
    CS: Bacreremia, Resp signs, Cardiovasc signs (grade 3-6/6 murmur)
18
Q

Bacterial endocarditis - ancillary and lab

A

o ECG, phonocardiography, echocardiography
o Aortic regurgitation —> diastolic, decrescendo murmur

o Leukocytosis, neutrophilia, hyperfibrinogenemia, hypergammaglobulinemia
o Blood culture (aseptic venous blood sample before starting AB treatment)

19
Q

Bacterial endocarditis - Dx and Tx

A

o Suspicion based on clinical signs, echocardiography

o AB: initially broad spectrum
o Treatment of congestive heart failure
o Antiarrhythmic drugs if necessary
o Flunixin meglumine
o Low molecular weight heparin
o Strict box rest

20
Q

Aortic valve insufficiency

A
  • Most common, older horses
  • Not always leading to exercise intolerance
  • Prolapse, nodules, thickening, fenestrations of valve leaflets
  • Holodiastolic, decrescendo, grade 3-6/6 murmur on left side
  • Strong, short pulse
  • Compensation: hypertrophy (stronger contraction stronger pulse), MVI, left atrial dilation, AF
  • Mosaic pattern = regurgitation
21
Q

Mitral valve insufficiency

A
  • Pan- or holosystolic murmur on left side, PMI: 5th ICS
  • Can continue to diastole: enhancement of 3rd heart
    sound, fast early filling
  • Acute/peracute MVI: ruptured chordae tendinea
  • Left atrial dilation, jet lesions (erosion development in
    atrial endocardium / endothelial abnormalities)
  • Echo on left side due to large heart and thickened chest
    wall
22
Q

Rupture of chorda tendinea

A
  • Peracute cardiac failure
  • Pulmonary edema: Can give huge amounts of digoxin - help pump function of the heart + large dose of furosemide
  • Grave prognosis
23
Q

Tricuspid and pulmonary valve insufficiency

A
  • Tricuspid valve insufficiency
    o Bacterial or secondary together with MVI
    o Systolic, grade 3-5 murmur of right side
    o Dilated jugular vein, positive venous pulse (due increased pressure/regurgitation into RV –> vena cava —> jugular vein)
  • Pulmonary valve insufficiency
24
Q

Atrial premature complex - Tx

A

Ausc, ECG

abnormal P-wave, narrow QRS,

Tx: Box rest, Arrhytmic drug (Quinidine, procainamide),
Dexamethadone
Correction of electrolytes

25
Q

Atrial fibrillation - Tx

A

Myocardial disease, not alter CO, cons of other cardiac disease

ECG: Variable, irregular RR intervals, No P wave, F wave instead
Tx: Quinidine, Digoxin

26
Q

Atrial flutter

A
  • Can be a stage after atrial fibrillation
  • Higher P wave
  • Lower contraction rate of atria compared to fibrillation
  • Can go to normal sinus rhythm
27
Q

Ventricular tachycardia - Tx

A
  • 4 or more consecutive VPCs, life-threatening, Fast HR

ECG: Abnormal QRS complex and T wave, QRS is independent from preceding P-wave, P wave may merge into QRS or T wave o “R-on-T” phenomenon - Torsades de pointes

Tx:
o Lidocaine IV
o Procainamide IV/PO
o Propranolol IV/PO
o Propafenone IV/PO
o Flecainide acetate IV
o Magnesium sulphate IV/nasogastric tube
o Bretylium IV