CV Risk Factors

Question 1

5 Causative (Major) CV RFs

Answer 1

Cigarette smoking
HTN
Hypercholesterolemia
Low HDL
Diabeetus

Question 2

2 Most Powerful RFs

Answer 2

Age and Diabetes

Question 3

Best Cholesterol Indicator of Risk

Answer 3

LDL/HDL Ratio

Question 4

Big Component of Why Diabetes such a Risk

Answer 4

Insulin resistance -> artherosclerosis

Question 5

HyperTG as RF

Answer 5

Its associations very bad: low HDL, insulin resistance, small dense LDL, glucose intolerance, HTN, obesity

Question 6

LDL Changes w/ Increasing TG

Answer 6

Ratio changes to more small, dense LDL which is worse

Question 7

Visceral Fat

Answer 7

Abdominal fat/waist circumference better indicator of CHF than BMI bc its the metabolically active fat

Question 8

Adipocytokines

Answer 8

Normal weight it produces adiponectin which is anti-artherogenic/diabetogenic, but as get too much there’s a switch from that production to inflammatory cytokines and stress and shit which is opposite

Question 9

Metabolic Syndrome

Answer 9

3+ of following: Abdominal obestiy/waist circumference, TG, HDL, BP, Fasting Glucose

Question 10

CRP

Answer 10

Measure of subclinical inflammation, production stimulated by IL-6. Great measure of risk for HD except fluctuates w/ any acute problems

Question 11

Lp(a) (again)

Answer 11

The “a” is a prot that competes w/ plasminogen, thus inhibiting fibrinolysis