CV 3 cerebrovascular disease Flashcards

1
Q

neurological deficit secondary to abnormal perfusion of brain tissue

A

stroke

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2
Q

permanent cerebrovascular disease

A

stroke

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3
Q

syncope has many causes and most cases resolve in –

A

one hour

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4
Q

stroke is the – cause of death

A

2nd

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5
Q

rate of stroke and TIA doubles after the age of –

A

55

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6
Q

ethnicity risk

A

twice for African Americans and Hispanics compared to whites

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7
Q

HTN increases risk

A

4x

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8
Q

diabetes and smoking increases risk

A

2x

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9
Q

can oral contraceptives increase risk?

A

yes

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10
Q

most strokes are

A

ischemic

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11
Q

transient loss of consciousness caused by a global decrease in cerebral perfusion

A

TIA

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12
Q

Cardiac syncope has the same causes as –

A

ischemic stroke (reduced CO)

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13
Q

– syncope may be preceded by autonomic symptoms like nausea, sweating, light-headedness

A

vasovagal

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14
Q

dehydration reduces intravascular volume leading to –

A

orthostatic syncope

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15
Q

reproducible vasovagal syncope caused by forceful urination, defecation, coughing

A

situational syncope

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16
Q

large artery stenosis

A

internal carotid, vertebral, basilar, branches of circle of Willis

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17
Q

in addition to larger artery stenosis, cardiac emboli, and small vessel disease what are other causes of ischemic stroke?

A
sickle cell disease
hypercoagulable states
drugs
birth control pills
(compromise blood flow)
18
Q

small vessel disease is characterized by –

A

endothelial damage (small lacunar infarcts in deep brain)

19
Q

subarachnoid hemorrhage involves bleeding into the subarachnoid spaces and –

A

cerebrospinal fluid

20
Q

intracerebral hemorrhage involves rupture of arteries and bleeding in the –

A

brain parenchyma

21
Q

diffuse hemorrhage

A

subarachnoid

22
Q

focal hemorrhage

A

intracerebral

23
Q

caused by aneurysms, vascular malformation, trauma, DIC

A

subarachnoid hemorrhage

24
Q

caused by hypertensive hemorrhage, use of anticoagulants esp in older patients

A

intracerebral hemorrhage

25
Q

brain is supplied with –

A

14% of CO

26
Q

brain utilizes –

A

10% of blood glucose

27
Q

most commonly affected artery for focal ischemia?

A

middle cerebral artery

28
Q

may initially see occipital headache, unsteady gait, ataxia, nausea and vomiting

A

hemorrhagic stroke

29
Q

differentiates between ischemic and hemorrhagic strokes

A

CT scan

30
Q

first line diagnostic test for ischemia

A

CT scan

31
Q

sensitive for detecting early ischemia

A

MRI

32
Q

MRI is used to see relationship with –

A

surrounding tissues

33
Q

perfusion scanning that shows under-perfused areas

A

MRI

34
Q

gold standard for diagnosing ischemia

A

cerebral angiography

35
Q

cerebral angiography evaluates –

A

large intracranial and extracranial blood vessels

36
Q

shows changing blood flow with neural activity

A

fMRI

37
Q

real time test to see which parts of brain are active

A

fMRI

38
Q

purpose of non-contrast CT

A

differentiate ischemic and hemorrhagic stroke

39
Q

although t-PA is the main treatment of ischemic stroke, newer therapies include

A

angioplasty and stenting (catheter-based therapies)

40
Q

evidence suggest that – is superior to medical treatment in cases of greater than 70% stenosis associated with symptoms such as TIAs

A

surgical carotid endarterectomy

41
Q

carotid endarterectomy removes – from carotid artery to restores blood flow to brain

A

atherosclerotic plaque