CRPD Flashcards
What are chronic restrictive lung diseases?
Pulmonary diseases characterized by reduced expansion of lung parenchyma along with decreased total lung capacity
How is CRPD characterized?
Reduced total lung capacity, vital capacity, or resting lung volume
Vital capacity in a patient with CRPD is (Decreased/Increased)?
Decreased
The FEV1/VC ratio in CRPD is (Decreased/Increased)?
Increased
Vital capacity in a patient with COPD is (Decreased/Increased)?
Normal
FEV1 in a patient with COPD is (Decreased/Increased)?
Decreased
The FEV1/VC ratio in COPD is (Decreased/Increased)?
Decreased
A patient with CRPD will have more trouble with (Inspiration/Expiration)?
Inspiration
What are the subtypes of CRPD?
Pneumoconiosis
Sarcoidosis
Goodpasture’s syndrome
What is pneumoconiosis?
Non-neoplastic lung reaction to inhalation of mineral dusts encountered in the workplace
What are the four subtypes of pneumoconiosis?
Anthracosis
Silicosis
Asbestosis
Berylliosis
How is anthracosis caused?
Carbon inhalation
What profession commonly gets anthracosis?
Coal miners
What is the other name for anthracosis?
Coal miners lung
How is silicosis caused?
Sand, cement, glass
What professions commonly get silicosis?
Construction work, stone masons, glassworkers
What is the number one cause of mesothelioma?
Asbestosis
How is asbestosis caused?
Asbestos
What professions can be asbestosis?
Installation pipefitters, steamfitters, Navy
What causes berylliosis?
Beryllium from aerospace air frame parts (Lockheed/Boeing)
Very long shards that cause macrophage lysis and the release of inflammatory mediators is indicative of what pneumoconiosis?
Asbestosis
What is sarcoidosis?
A granulomatous disease of unknown etiology
What type of atelectasis is caused by sarcoidosis?
Compression atelectasis
There is no mediastinal shift in the atelectasis caused by sarcoidosis (TRUE/FALSE)?
TRUE
What is the most commonly involved organ for sarcoidosis?
Lung
Non-caseating granulomas and potato nodules bilaterally on the bronchi that resolve with prednisone is indicative of what pathology?
Sarcoidosis
What is Goodpasture’s syndrome?
Type II hypersensitivity reaction where the body makes an antibody against a fixed antigen on the basement membrane of the kidney and lungs
Patient presents coughing up blood and marked weakness in his muscle testing. The patient also reports peeing blood. Radiography demonstrates a diffuse bilateral alveolar infiltrate. Blood panel shows an antibody against the glomerular basement membrane. What is the likely diagnosis?
Goodpasture’s syndrome
What is the difference between a type II and type III hypersensitivity reaction?
Type II = Ab against a fixed antigen
Type III = Ab against a soluble antigen
