CRPD Flashcards

1
Q

What are chronic restrictive lung diseases?

A

Pulmonary diseases characterized by reduced expansion of lung parenchyma along with decreased total lung capacity

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1
Q

How is CRPD characterized?

A

Reduced total lung capacity, vital capacity, or resting lung volume

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2
Q

Vital capacity in a patient with CRPD is (Decreased/Increased)?

A

Decreased

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3
Q

The FEV1/VC ratio in CRPD is (Decreased/Increased)?

A

Increased

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4
Q

Vital capacity in a patient with COPD is (Decreased/Increased)?

A

Normal

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5
Q

FEV1 in a patient with COPD is (Decreased/Increased)?

A

Decreased

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6
Q

The FEV1/VC ratio in COPD is (Decreased/Increased)?

A

Decreased

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7
Q

A patient with CRPD will have more trouble with (Inspiration/Expiration)?

A

Inspiration

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8
Q

What are the subtypes of CRPD?

A

Pneumoconiosis
Sarcoidosis
Goodpasture’s syndrome

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9
Q

What is pneumoconiosis?

A

Non-neoplastic lung reaction to inhalation of mineral dusts encountered in the workplace

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10
Q

What are the four subtypes of pneumoconiosis?

A

Anthracosis
Silicosis
Asbestosis
Berylliosis

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11
Q

How is anthracosis caused?

A

Carbon inhalation

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12
Q

What profession commonly gets anthracosis?

A

Coal miners

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13
Q

What is the other name for anthracosis?

A

Coal miners lung

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14
Q

How is silicosis caused?

A

Sand, cement, glass

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15
Q

What professions commonly get silicosis?

A

Construction work, stone masons, glassworkers

16
Q

What is the number one cause of mesothelioma?

A

Asbestosis

17
Q

How is asbestosis caused?

A

Asbestos

18
Q

What professions can be asbestosis?

A

Installation pipefitters, steamfitters, Navy

19
Q

What causes berylliosis?

A

Beryllium from aerospace air frame parts (Lockheed/Boeing)

20
Q

Very long shards that cause macrophage lysis and the release of inflammatory mediators is indicative of what pneumoconiosis?

A

Asbestosis

21
Q

What is sarcoidosis?

A

A granulomatous disease of unknown etiology

22
Q

What type of atelectasis is caused by sarcoidosis?

A

Compression atelectasis

23
Q

There is no mediastinal shift in the atelectasis caused by sarcoidosis (TRUE/FALSE)?

A

TRUE

24
Q

What is the most commonly involved organ for sarcoidosis?

A

Lung

25
Q

Non-caseating granulomas and potato nodules bilaterally on the bronchi that resolve with prednisone is indicative of what pathology?

A

Sarcoidosis

26
Q

What is Goodpasture’s syndrome?

A

Type II hypersensitivity reaction where the body makes an antibody against a fixed antigen on the basement membrane of the kidney and lungs

27
Q

Patient presents coughing up blood and marked weakness in his muscle testing. The patient also reports peeing blood. Radiography demonstrates a diffuse bilateral alveolar infiltrate. Blood panel shows an antibody against the glomerular basement membrane. What is the likely diagnosis?

A

Goodpasture’s syndrome

28
Q

What is the difference between a type II and type III hypersensitivity reaction?

A

Type II = Ab against a fixed antigen
Type III = Ab against a soluble antigen