Critical Care Drugs Flashcards
Four categories of shock
-Obstructive (pulmonary/vascular blockage)
-Distributive (crazy vasodilation)
-Cardiogenic (not pumping blood)
-Hypovolemic (loss of blood volume)
1st line of treatment for shock?
IV fluids
Name where Alpha 1, alpha 2, beta 1, and beta 2 receptors are located
-alpha 1: sm muscle
-alpha 2: brain
-beta 1: heart
-beta 2: lungs
When activated, a1/2 and b1 receptors cause _______. Beta 2 receptors cause _______.
-vasoconstriction
-bronchodilation
Chronotropes affect heart _____, while inotropes affect…
-rate
-strength of heart muscle contraction
Drugs that work ONLY on Alpha 1
-phenylephrine
-dopamine
-midodrine
Drug that works on Alpha 1 and alpha 2 receptors (plus a little beta 1)
norepinephrine
Epinephrine activates what receptors?
-Beta 1, beta 2, alpha 1
dobutamine affects _____ __ receptors ONLY
Beta 1
dopamine works only on _____ __ receptors
alpha 1
vasopressin
Alpha-adrenergic drugs (EX) side effects
HYPERTENSION, chest pain, bradycardia, N/V, anorexia, palpitations
Epinephrine SFX
-hypertension, tachycardia, hyperglycemia
dobutamine and epinephrine can both cause…
tachycardia
Midodrine is a ___drug that works on the _____-__ receptors. It’s given for __________ hypotension, so it shouldn’t be given before lying down to prevent ________ ___________.
Midodrine is a prodrug that works on the alpha-1 receptors. It’s given for orthostatic hypotension, so it shouldn’t be given before lying down to prevent supine hypertension.