Antivirals, Antifungals, and Antineoplasts Flashcards
Ticonazole (Vagistat), miconazole, and clotrimazole are all ______ antifungals and can are common ___ meds.
topical, OTC
Amphotericin B (AKA ________) will cause what side effects (including what organ toxicity? What would you give in anticipation of these effects? What labs would you monitor?
“amphoterrible”
-fever, chills, nausea/vomiting, low BP, tachycardia
-nephrotoxicity
-premedicate w/ antihistamine, antipyretic, anti-nausea meds
-monitor renal labs like BUN/creatinine
Nystatin is used to treat _____
thrush (oral candidiasis)
What are HSV1/2 treated with? Can these viruses be cured?
-acyclovir/valacylovir
-no, just managed/treated
How many times per day would you take acyclovir? How many times would you take valacyclovir per day?
-acyclovir: 5x day
-valacyclovir: 1x day
HSV3, or varicella zoster (chickenpox), can be prevented with:
the childhood varicella vaccine
What patients are at risk for HS5 (CMV)?
Severely immunocompromised patients (i.e., organ transplant recipients)
There are 3 types of hepatitis. Which ones have a preventative vaccine?
Hep A and Hep B have a vaccine, Hep C does not.
How is Hep C spread? How is it treated (+ who cannot have that med)?
-sexual contact–blood, fluid
-Ribavirin–which is a teratogen, so pregnant people can’t have it!
Name the Hep B preventative vaccine and post exposure treatment
-HBV vaccine (x3)
-immunoglobulins w/in 3 weeks of exposure
Name the Hep A preventative vaccine and post exposure treatment
-HAV vaccine
-immunoglobulin GamaSTAN
How is Hep A spread vs Hep B/C?
A: oral-fecal route
B/C: blood, body fluids
Oseltamivir treats what if taken w/in 48 hours of symptom onset?
It has what side effect?
-Influenza A, B
-Nausea, vomiting
Ganciclovir and valganciclovir treat…
CMV
Folate, purine, and pyrimidine antagonists are all:
antimetabolite atineoplasts
