CPP Aspirin

Question 1

Aspirin

Presentations

Answer 1

a) 300mg chewable tablets

b) 300mg soluble or water dispersible tablet

Question 2

Aspirin

Primary emergency indications

Answer 2

a) Chest pain/discomfort,
b) Acute Coronary Syndrome (ACS).

Question 3

Aspirin

Contraindications
(Known hypersensitivity plus)
CHHESSA

Answer 3

a) Chest pain assoc w psychostimulant OD, if SBP >160mmHg,
b) Haemophilia or other bleeding disorders,
c) Hypersensitivity to other salicylates,
d) Erosive actively bleeding gastritis or peptic ulcer,
e) Suspected dissecting aortic aneurysm,
f) Severe hepatic or renal disease,
g) Acute febrile illness in children and adolescents.

Question 4

Aspirin

Precautions

Answer 4

1. Active peptic ulcer,
2. Asthma,
3. Anticoagulant use.

Question 5

Aspirin

Key timings

Answer 5

Onset: N/A for emerg presentations,
Peak: N/A,
Duration: 8-10 days.

Question 6

Aspirin

Special notes/Important interactions

Answer 6

NOT to be administered for any condition OTHER THAN chest pain/discomfort of a CARDIAC nature.

Question 7

Aspirin

Pharmacology/Actions

Answer 7

Analgesic, antipyretic, anti-inflammatory and anti-platelet aggregation agent.

Used to minimise platelet aggregation & thrombus formation, to retard the progression of coronary artery thrombosis in ACS.

Also, inhibits synthesis of prostaglandins, and had anti-inflammatory actions.