Contraception; LARC and Non-LARC Flashcards
What affects the choice of contraception?
Effectiveness Control Long/short term Non-contraceptive benefits Procedure
What are the different forms of CHC?
Pill
Patch
Vaginal ring
What is the failure rate of CHC?
Perfect = 0.3%
Typical - 9%
How should the COC be taken?
Start in first 5 days of period; this will provide immediate contraceptive cover
OR
At any time in cycle when sure not pregnant BUT need condom use for 7 days
What is a tailored COC regimen?
Used continuously or have a pill free interval for less than 7 days
What is tricycling?
Off use COC use
Run 3 packets then withdrawal
May have breakthrough bleeding
What is continuous COC use?
Continually use pill
When breakthrough bleeding occurs; stop for 4 days and then start again
What factors affect the effectiveness of CHC?
Impaired absorption; GI conditions such as crohn’s or US
Enzyme inducing drugs
Forgetting
What are the 3 main risks of CHC?
Venous thrombosis
Arterial thrombosis
Adverse effects on breast ca
What is the increased risk assoc with COC and VTE?
Increased according to EE dose and progesterone type
Non-pregnant; 2 per 10,000 women per annum
3rd generation progesterone (gestodene, desogesterol); around 9-12 per 10,000 women
What is the VTE risk in pregnancy per 10,000 per annum?
21-30
What is the VTE risk in the first few weeks postnatally per 10,000 women per annum?
13-140
What advice is there surrounding VTE and COC?
Prescribe most effective CHC with lowest risk
Tell patients signs and symptoms of VTE (hot, swollen leg, breathlessness, chest pain etc)
What circulatory arterial effects can CHC have?
Systemic hypertension
Small increase in BP therefore must check initially, at 3 months then annually
Is there an increased risk of MI in CHC use?
Slightly, particularly smokers
Increased risk of ischaemic stroke
Hypertensive COC (systolic >160 mmHg or diastolic <95 mmHg) are at higher risk
What is an absolute contraindication to CHC use?
Migraine with aura ; massively increases risk of ischaemic stroke
What is an aura?
Change occuring 5-20 mins before onset of headache May be visual, typical scotoma Altered sensation Smell or taste Hemiparesis
Should you prescribe CHC in those over 35?
Relative CI; benefits still outweigh risk but consider something else
What cancer’s can CHC increase the risk of?
Breast
1.24 increased relative risk whilst using, reducing to baseline 10 years after stopping
If there is a family history of breast cancer, think about it
Small increased risk of cervical cancer with long term use
What can be done to reduce the risk of cervical cancer?
HPV (16 and 18) vaccine
Up to date with cervical screening
What examination is performed before prescription of CHC?
BP and BMI
Smear status if relevant
Discuss risk factors; family history of VTE or inherited thrombophilia, breast or cervical cancer, hypertensive, migraine with aura
What cancers will CHC be protective against?
20% reduction in ovarian cancer for every 5 years with a maximum 50% reduction after 15 years use
20-50% reduction in endometrial ca
12% reduction in all-cause mortality and no overall increased risk of ca
Which pill has the greatest effect on acne?
EE/cyproterone acetate which is an antiandrogen/progestagen and antiglucocorticoid
What is the downfall with dianette?
Higher risk of blood clot
What other non-contraceptive benefits can be seen from CHC aside from acne?
Less bleeding
Fewer functional ovarian cysts
Premenstrual syndrome
PCOS
Common side effects of CHC?
Nausea
Spots
Breast tenderness
Bleeding
What is the difference between COC and POP?
POP you take EVERY DAY with no break, even if you start to bleed you continue to take
How can progesterone only methods be administered?
POP
Subdermal implant
DMPA
When should you start progesterone only methods?
Day 1-5 of period
Anytime if reasonably certain not pregnant plus condoms for 7 (2 for POP) days
What are the risks assoc with POP and subdermal implant?
Little effect on metabolism
Can be given in most circumstances
Safer than pregnancy
UKMEC4 in current breast ca
How frequently is depot progesterone given?
Every 3 months
High change of amenorrhoea
What are the downsides to depo provera?
Lowers estradiol and suppresses FSH
Can result in osteopenia/ osteoporosis
If on POP for a long time, consider DEXA scan
Advice weight bearing exercises and high calcium intake
Are condoms a good method for contraception?
No; high failure rate
Use for STI prevention
What is the effectivity rate for the diaphragm?
71-88% with typical use
How is a diaphragm used?
Spermicide on rim and entered into vagina
Dome sits underneath the pubic bone