Common variable immune defiicienty Flashcards

1
Q

Presentatie CVID

A

Boven de 4 jaar
Hypoglobulinemie (verlaagd IgM, IgG, IgA)
Infecties
Vaak ook niet-infectieuze complicaties (-> bronchiectasieen)
Afwezigheid vaccinatieresponsen

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2
Q

Immunologisch onderzoek CVID

A

verlaagde memory B-cellen, met name verlaagde geswitchte memory B-cellen

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3
Q

Prognose CVID

A

Verminderde overleving door chronische ziekte. Bij alleen infectieuze complicaties is overleving excellent

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4
Q

Manieren van toedienen immuunglobulines

A

> intraveneus immunoglobuline (IVIG)
F-SCIG - fascilitated sub cutane immuno globuline
SCIG - sub cutane immunoglobuline

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5
Q

IVIG

A

Intraveneus immunoglobuline

  • 1x in de 3-4 weken door verpleegkundige
  • Schommelingen in waarden en iets vaker reacties
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6
Q

F-SCIG

A

Fascilitated sub cutaan immunoglobuline
1. Hyaluronidase en 2. immunoglobuline
1x in de 3-4 weken

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7
Q

SCIG

A

Sub cutane immunoglobuline
1x per week
Stabielste spiegels

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