Collagen Flashcards
Mesenchymal Connective Tissue
in embryo/ fetus
has reticular fibers and mesenchymal cells
becomes diff types of CT
Mucous Connective Tissue
matrix w/ collagen fibers and fibroblasts
in umbilical cord (as Wharton jelly) and other developing structures
Supporting Connective Tissue
cartilage and bone
Hematopoietic Tissue
Blood and bone marrow
Fixed Cells
fibroblasts
stay in CT
Wandering Cells
eosinophils, mast, plasma cells
travel within tissue
Fibroblasts
main cell in CT
make procollagen
Most common type of collagen
Type 1
90% of all collagen
Fibrous Collagen
25 nm (cornea) - 200 nm (skin/ tendon) Type 1, 2, 3
Non-fibrous Collagens
25 nm (capillaries and glomeruli) - 200 nm (lens capsule)
Type 4
in all basement membranes
Filamentous Collagens
form loosely aggregated fibers w/ little or no pattern
pericellular or matrix collagens
Type 6, 7, 9, 10
Cornea
transparent tissue w/ fine collagen fibers of same diameter w/ great amount of organization
Type 1, 5
Sclera
opaque tissue w/ thick interwoven collagen fibers
30nm - 300nm
Type 1, 3
Vitreous Body
gel w/ small amounts of fine CF (7- 13nm)
Type 2
Lens Capsule
has amorphous basement membrane structure
Type 4
Choroid
highly vascularized tissue of iris
Vitreous Function
maintain IOP and act as shock absorber
Fibers of Vitreous
stabilize shape of gel
reduce compressibility of gel
Descemet’s Membrane
separates corneal stroma from corneal epithelium
Type 4, 8
Retina
Type 4
Type 6
cornea and corneal stroma
made by corneal endothelial cells
filamentous collagen
Type 8
Descemet’s
filamentous
Type 9
vitreous
filamentous
Corneal Strength
depends on cross linking of collagen fibers in head to tail orientation
