Biochemistry Intro Flashcards
Acid + Alcohol
Ester
Acid + Thiol/Sulfhydril
Thioester
Acids + Amines
Peptides or Amides
Phosphoric Acid + Alcohol
Phosphomonoesters
Condensation of 2 Acids
Anhydride
Release of O2 from hemoglobin requires…..
Histidine
Acids
donate protons
Bases
Accept protons
Covalent Bonds
Sharing of electrons
Non-Polar Covalent Bonds
electrons shared equally
Polar Covalent Bonds
Atom with greater electronegativity has greater pull; electrons shared unequally
C : (O+N) = 1-3
Very Soluble
C : (O+N) = 3-6
Soluble
C : (O+N) > 6
Insoluble
Phosphate Transfer
Transferring a phosphate group from ATP to another molecule
Forms phosphomonoester bonds
Process aided by kinases
Phosphate Cleavage
Phosphatases hydrolyze phosphomonoester bonds to remove a phosphate group
Rearrangement Reaction
Change in structure results in a new compound
Condensation Reaction
Removing 2H and 1O to make a single new compound + water
Hydrolysis
Adds H20 and splits apart a compound
Oxidation-Reduction Reactions
OIL RIG (electrons)
Dehydrogenase
Removes 2H from substrate
in oxidation-reduction
Oxidase
promotes the gain of O in oxidation-reduction
Reductase
Add 2H to substrate
Lower pKa =
Stronger Acid
pH = pKa
Conj. Base = Acid
pH > pKa
Conj. Base > Acid
pH
Conj. Base