CNS Flashcards

1
Q

What are focal neurological signs?

A

A set of symptoms in which causation can be localised to an anatomic sight in the CNS.

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2
Q

What are generalised neurological abnormalities.

A

An alteration in levels of consciousness.

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3
Q

What are the signs of frontal lobe damage?

A

Anosmia (loss of smell)
Inappropriate emotions.
Excessive dysphasia- loss of speech.
Motor impairment.

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4
Q

What are the signs go parietal lobe damage?

A

Receptive dysphasia

Sensory impairment.

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5
Q

What are the signs of temporal lobe damage?

A

Cortical deafness.

Receptive dysphasia.

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6
Q

What is cerebrovascular disease?

A

A leading cause of mortality and morbidity.

Caused by either hypoxia, ischaemia, infarction and haemorrhage.

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7
Q

Tissue survival during cerebrovascular disease is dependent on?

A

Collateral circulation
Duration of ischaemia
And magnitude of flow reduction.

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8
Q

How would you recognise the signs of stroke?

A

Facial drooping
Inability to raise arms due to weakness and numbness.
Slurred speech- dysarthria
Loss of function that lasts over24 hours.

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9
Q

What is a transient ischaemic attack?

A

A mini stroke
Usually resolves in 24 hours.
Symptoms are similar to a full stroke.

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10
Q

What are the risk factors of stroke?

A
Hypertension
Diabetes
Previous TIA
Heart disease
Hyperlipidaemia.
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11
Q

What are the symptoms of a left MCA infarct?

A

Damage to the speech in L hemisphere- loss of speech (aphasia)
Damage to L visual pathway- Loss of R vision- hamianopia.
Damage to left motor cortex and internal capsule- weakness of right fact, arm and leg.

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12
Q

What causes haemorrhagic events?

A
Hypertension
Berry aneurysm
Neoplasia
Trauma
Drug abuse
Iatrogenic.
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13
Q

Explain intracerebral haemorrhage.

A

Most are hypertension bleed- capsular haemorrhage.

Presents with headache, rapid or gradual decrease in conscience.

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14
Q

Explain Subarachnoid haemorrhage

A

Rupture of saccular aneurysms.
Results in thunderclapping headache.
Symptoms similar to meningitis.

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15
Q

Explain subdural heamorrhage.

A

Fluctuating levels of conscience.
Often on anticoagulants.
Often occurs as a result of minor trauma in the elderly.

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16
Q

Explain extradural haemorrhage.

A

Post head injury resulting in slow falling conscious levels. Lucid period.
Often occur with a fractured temporal or parietal bone.

17
Q

What are the signs of dementia?

A

Increased risk of over 65.
Memory loss
Reduced speed of thought
Language change

18
Q

How would you test for dementia?

A

TSH- check thyroid levels are normal.
CT scan
Vitamin b12 thiamine.

19
Q

Explain the symptoms of alzheimers disease.

A

Defects in the visual-spatial skills (get lot)
Memory loss
Decreasing cognition
Ansognosia- lack of awareness

20
Q

What are the symptoms of epilepsy?

A

Focal twitching
Trance-like
Convulsions.

21
Q

Explain meningitis.

A

A bacterial infection.
Early symptoms include headache, cold and and feet, pyrexia.
Late signs include neck stiffness, photophobia, kerning’s sign (knee pain),
non blanching rash.

22
Q

Explain brain abcesses.

A

Focal infection.

Presents with headache, seizures and pyrexia.

23
Q

Explain parkinson’s disease.

A

Movement disorder- can be sporadic or familial.
Drug induced by haloperidol.
Presents as rigidity, bradykineses, resting tremor and postoral instability.

24
Q

Explain meningiomas.

A

Slow growing benign brain tumour..

25
Q

Explain astrocytomas.

A

Brain tumours that range in severity. Usually fatal.

26
Q

Explain pituitary tumours.

A

Can cause compression symptoms- such as affecting the eye.
Hormone active- secrete hormones.
E.g prlactinoma causes an increase in prolactin- resulting in an increase in nipple discharge.