CMV2 Flashcards
1
Q
What are uses for Letermovir
A
prophylaxis of CMV reactivation
in HSCT recipients who are CMV+, receiving a transplant from any donor
If HSCT recipient CMV-, they will instead receive valganciclovir
2
Q
What is dose of letermovir
What is duration of letermovir
A
480mg OD
100 days
Costs £3000
3
Q
What is mechanism of action of letermovir
A
Letermovir is a cytomegalovirus DNA terminase complex inhibitor that interferes with cytomegalovirus genome formation and virion maturation
