CMV

Question 1

number

Answer 1

HHV type 5 (cytomegalic inclusion disease)

Question 2

newborns percent

Answer 2

1% of newbornds.

90%- asymptomatic.

Question 3

manif.

Answer 3

Jaundice 
hepatosplenegaly 
cerebral calcification. 
chorioretinitis 
microcephaly 
mental retardation 
deafness

Question 4

cutaneous manif

Answer 4

Result from theombocytopenia:
Petechiae purpura ecchymosee.
purpuric lesions - macular papular or nodular may show extramedullary hematopiesis (dermal erythropoiesis) Prod “blue berry muffin baby”

Question 5

most symptomatic cases occur

Answer 5

within 2 mos of life.

Question 6

Ampicilli and amoxicillin admin will often result in

Answer 6

Morbilliform eruption in acute cmv infection.

Question 7

CMV infectijg endothelial cells may prod-

Answer 7

vasculopathu in cmv viremic or partially reactivating patients.
lead to prominent vadculopathic changes inc reynaud phenomenon deep venous thrombosis digital gangrene and reticulated purpura.

Anti cardiolipin antibodies may be positive.
Anti CMV tx Can reverse the syndrome and clear the anticardiipin antibodies.