Clinical Abx (lecture)

Question 1

What are the 4 most common causes of neonate meningitis?

Answer 1

GBS, E. coli, Listeria, Gram negative rods

Question 2

What are the 2 most common causes of meningitis in 2 - 50 y.o.?

Answer 2

Neisseria and Strep pneumoniae

Question 3

What are the 4 most common causes of meningitis in > 50y.o.?

Answer 3

Strep pneumoniae, Neisseria, Listeria, Gram neg. rods

Question 4

What are the 5 broad spectrum G+ and G- Abx mentioned in lecture?

Answer 4

Ampicillin, Azithromycin, Amoxicillin-clavulanate, Cefepime, Imipenem

Question 5

What Abx is used for anaerobic below the diaphragm?

Answer 5

Metronidazole

Question 6

What Abx is used for anaerobic above the diaphragm?

Answer 6

Clindamycin

Question 7

What class of Abx is used for general anaerobic infections?

Answer 7

Carbapenems

Question 8

What drugs are used for intracellular organisms?

Answer 8

Macrolides, Tetracyclines, Fluoroquinolones, Sulfa/trimethoprim, Rifampin
Note: They target gene expression directly or indirectly

Question 9

What is the first line in MRSA?

Answer 9

Vancomycin

Question 10

What are the bacteriostatics?

Answer 10

Erythromycin, Tetracycline, Sulfa, Chloramphenicol, Clindamycin

Question 11

What is the first line treatment of MSSA?

Answer 11

Oxacillin