Class 9 Flashcards
What is the phenomenon of pacemaker cells with higher intrinsic rhythm preventing latent pacemakers in the heart from firing
Overdrive Suppression
Pacemaker cells with higher intrinsic rhythm tend to suppress what?
Latent pacemaker’s automaticity
When is the automaticity of pacemaker cells depressed?
When they are forced to fire faster than their intrinsic rate
What is the mechanism of overdrive suppression?
The activity of the Na/K ATPase increased when Na has a higher rate of influx, creating a higher rate of Na efflux than K influx
When overdrive suppression has happened it is more (negative, positive) in the cell
Negative, hyperpolarization
When it is more negative in the pacemaker cell, what happens to the pacemaker’s automaticity?
It is suppressed
When a pacemaker cell is hyperpolarized, the diastolic potential is changed how?
More negative maximum diastolic potential
When a pacemaker cell is hyperpolarized, what happens to the threshold value?
It is increased, thus slowing automaticity
What is a phenomenon that cardia impulses may re-excite the myocytes through which it had passed previously within same cardia cycle?
The re-entry loop
What is a direct consequence of conduction disturbance?
Onset of tachycardia or fibrillation
3 essential conditions required for the re-entry loop:
1) Must be closed conduction loop
2) Must be region of unidirectional block
3) Slow conduction of impulse around the loop
What does the re-entry loop cause physically to happen?
An extra heart beat
SA node controls the cardiac rhythm describes what?
Sinus rhythm
Sinus rhythm with a rate less than 60 bpm describes what?
Sinus bradycardia
Sinus rhythm with a rate greater than 100 bpm describes what?
Sinus tachycardia
Defined as the onset of abnormal heart rhythms is what?
Arrhythmia
Prolonged impairment of SA node allows latent pacemaker (AV node) to initiate escape beat is what?
Escape rhythm
Continuation of escape beats gives ride to what?
Escape rhythm
What is more sensitive to parasympathetic activity? SA and AV nodes or ventricular conducting system
SA and AV nodes
What is the ventricular conduction system?
bundle of His or bundle branches
During intense parasympathetic activity what becomes the latent pacemaker? When would this happen?
Ventricular conduction system, this is an escape rhythm