class 5: other systems Flashcards
what is Metabolic syndrome
consists of signs and symptoms that are risk factors and are strongly linked to type 2 diabetes, cardiovascular disease, and stroke.
Metabolic syndrome diagnosis parts
Waist circumference
Triglycerides
High Density Lipoprotein (HDL)
Blood Pressure
Fasting Plasma Glucose
Metabolic syndrome diagnosis - Waist circumference
> 40 inches in men or > 35 inches in women
Metabolic syndrome diagnosis - Triglycerides
150 mg/dL or higher
Metabolic syndrome diagnosis - High Density Lipoprotein (HDL)
< 40 mg/dL in men or < 50 mg/dL in women
Metabolic syndrome diagnosis - Blood Pressure
Systolic 130 mm Hg and/or diastolic BP = 85 mm Hg
Metabolic syndrome diagnosis - Fasting Plasma Glucose
> 100 mg/dL
is HDL or LDL better
HDL good
LDL bad
Hypothalamus function
responsible for regulation of the ANS (body temperature, appetite, sweating, thirst, sexual behavior, rage, fear, blood pressure, sleep)
Pituitary gland function
secretes endorphins and reduces a person’s sensitivity to pain.
It controls ovulation and works as a catalyst for the testes and ovaries to create sex hormones
Thyroid gland function
produces hormones that act to control the rate at which cells
burn the fuel from food
Parathyroid gland function
regulate calcium and phosphate metabolism
Adrenal gland function
produces corticosteroids that will regulate water and sodium
balance, the body’s response to stress, the immune system, and metabolism
what is Addison’s Disease
Adrenal insufficiency – decreased cortisol and aldosterone
what causes Addison’s Disease
infections, neoplasm, hemorrhage,
autoimmune process.
Addison’s Disease - BP and hydration
Decreased BP, dehydration
Addison’s Disease - glucose
Decreased glucose
Addison’s Disease - skin
Bronze pigmented skin – increased MSH
Addison’s Disease - weight
Weight loss, anorexia, GI disturbances
Addison’s Disease - muscles
Generalized weakness (asthenia)
Addison’s Disease - tolerance
Intolerance to cold and stress, anxiety and depression
what is Cushing’s Disease
Elevated cortisol and aldosterone
what causes Cushing’s Disease
pituitary tumor with increased ACTH secretion
Cushing’s Disease - BP and hydration
Increased BP, water retention
Cushing’s Disease - CA
Hypokalemia
Cushing’s Disease - glucose
increased glucose
Cushing’s Disease - skin
Ruddy appearance, striae on skin
Cushing’s Disease - weight
Weight gain, centripetal obesity, round moon face
Cushing’s Disease - muscle strength
Proximal muscle weakness and atrophy
Cushing’s Disease - tolerance
Increased susceptibility to infection, osteoporosis (buffalo hump), poor wound healing
Cushing’s Disease vs. Cushing’s Syndrome
Cushing’s Disease: Pituitary Adenoma → more ACTH secreted by
PITUITARY GLAND → stimulates Adrenal gland → more CORTISOL
is released
Cushing’s Syndrome: Adrenal gland tumor → Adrenal gland
secretes more CORTISOL → drug toxicity
sym are common in both
what are the two thyriod problems
hyperthyroidism and hypothyroidism
what are the two adrenal cortex problems
cushing and addison’s
what is Hyperthyroidism 2/2
Increased T3 and T4, low TSH
what is the function of cortisol
- regulate BP
- glucose formation
- stress response
- decreases inflammation
what is the function of aldosterone
kicks out K
matains NA and H2O
Hyperthyroidism - HR and heat
HR increase
heat intolerance
Hyperthyroidism -glucose and GI, weight
Increased glucose absorption
Diarrhea
weight loss and decreased appeitite
Hyperthyroidism - sweat
Increased perspiration
Hyperthyroidism - what are example of these disease
Exophthalmos, Graves’ disease