Chp. 14 Lymphatic and Immune Flashcards
What is the open, incomplete circulatory system that moves fluid slowly in one direction?
Lymphatic system!
Small lymph capillaries interact with _____ ___________ in interstitial spaces in tissues
blood capillaries
What happens to fluid from body tissues?
It enters the lymph capillaries and is drained
What do macrophages do?
phagocytose foreign substances
What do B lymphocytes do and where do they originate?
Produce antibodies, mature in bone marrow
What do T lymphocytes do and where do they originate?
Attack bacteria and foreign cells, originate in the thymus gland
What does the spleen do? (4)
- Destroys old red blood cells
- Filters microorganisms and other foreign material out of the blood
- Activates lymphocytes during blood filtration
- Stores RBCs and platelets
What does the thymus gland do? (2)
- Provides immunity in fetal life and in early years of growth
- Makes cells immunocompetent in early life
Early removal of the thymus gland from an animal has what result?
Impairs ability to make antibodies and ability to produce cell to fight antigens
Vocab: Leukocytes (list of 3)
neutrophils, monocytes, and macrophages
Vocab: Lymphoid organs (list of 5 AND function)
- lymph nodes
- spleen
- thymus gland
- tonsils
- adenoids
**produce lymphocytes and antibodies
Vocab: Immunity
the body’s ability to resist foreign organisms and toxins that damage tissues and organs - can be natural or adaptive
Vocab: Natural Immunity
resistance that is present at birth and NOT dependent of prior exposure to an antigen
Cells of natural immunity:
Macrophages
NK cells
**phagocytosis!
Vocab: Humoral adaptive immunity
Involves B cells that produce lymphocytes and mature into plasma cells
Vocab: Cell-mediated adaptive immunity
involves T cells (cytotoxic and helper)
Does T cell function involve antibodies?
Nope (but like kinda?)
Which T cells attach to and directly kill antigens?
Cytotoxic T cells
Which T cells promote antibody synthesis by B cells and stimulate by B cells and stimulate other T cells?
Helper T cells
Which T cells inhibit B and T cells and prevent them from attacking the body’s own good cells?
Suppressor T cells (Tregs)
Vocab: dendritic cells (origin and 2 functions)
- macrophage derived from monocytes
- recognize and digest foreign antigens
- present antigens on the surface to stimulate B and T cells
multiple copies of cells or genes that kill tumor cells (passive immunotherapy)
Monoclonal antibodies (MoAb)
contain antigens from the patient’s tumor cells, stimulate the patient’s own T cells to recognize and kill the cancerous cells, active immunotherapy
Vaccines
In bone marrow transplantation, T lymphocytes from a donor can replace a patient’s immune system with new cells that recognize tumor cells as foreign and kill them
Immune cell transfer