Chp 14- Blood Lymphatic and Immune Flashcards
macrophages
phagocytose foreign substances
B lymphocytes (B cells)
produce antibodies; mature in the bone marrow
T lymphocytes (T cells)
attack bacteria and foreign cells; originate in the thymus gland
natural immunity
resistance present at birth; not dependent on prior exposure to an antigen
adaptive immunity
body’s ability to recognize and remember specific antigens in an immune response
Monoclonal antibodies (MoAb)
multiple copies of cells or genes that kill tumor cells; passive immunotherapy
vaccines
contain antigens from the patients tumor cells; stimulate the patients own T cells to recognize and kill the cancerous cell’s active immunotherapy
(IGNORE)transfer of immune cells
in bone marrow transplantation, T lymphocytes from a donor can replace a patients immune system with new cells that recognize tumor cells as foreign and kill them
adenoids
mass of lymphatic tissue in the nasopharynx
axillary nodes
lymph nodes in the armpit
cell-mediated immunity
T cells that respond to antigens and destroy them
cervical nodes
lymph nodes in the neck region
complement system
proteins in the blood that help antibodies and kill their target
cytokines
proteins secreted by cytotoxic T cells to aid in antigen destruction
cytotoxic T cell (CD8+ T cell)
lymphocyte that directly kills antigen
dendritic cell
antigen-presenting cell; shows T and B cells what to attack
Helper T cell (CD4+ T cell)
lymphocyte that aids B cells and stimulates T cells
humoral immunity
B cells produce antibodies after exposure to specific antigens; type of adaptive immunity
immunoglobulins
antibodies secreted by plasma cells in response to the presence of an antigen
inguinal nodes
lymph nodes in the groin region
interferons
proteins screted by T cells and other cells to aid and regulate the immune response
interleukins
proteins that stimulate the growth of B and T lymphocytes
lymph
thin, watery fluid within lymphatic vessels and collected from tissues throughout the body
lymph capillaries
tiniest lymphatic vessels
lymphoid organs
lymph nodes, spleen, thymus gland
lymph node
collection of stationary solid lymphatic tissue along lymph vessels
lymph vessel
carrier of lymph throughout the body
macrophage
large phagocyte found in lymph nodes and other tissues of the body
mediastinal nodes
lymph nodes in the area between the lungs in the thoracic cavity
mesenteric nodes
lymph nodes in the mesentery
monoclonal antibody
antibody produced in a lab to attack antigens and to destroy cells
paraaortic nodes
lymph nodes near the aorta in the lumbar area of the body
plasma cell
lymphocyte that secretes antibodies; matures from B lymphocytes
right lymphatic duct
vessel in the chest that drains lymph from the upper right part of the body; empties onto large neck vein
spleen
organ in left upper quadrant of the abdomen that destroys worn-out RBCs, activates lymphocytes, and stores blood
suppressor T cell (Treg)
lymphocyte that inhibits the activity of B and T cells
T cell (T lymphocyte)
lymphocyte that acts directly on antigens to destroy them or produces chemicals toxic to antigens
tolerance
ability of T lymphocytes to recognize and accept the body’s own antigens as self or friendly
Thoracic duct
drains lymph from lower and left side of body; empties into large veins in neck
thymus gland
lymphoid organ in mediastinum that conditions T cells to react to foreign cells
tonsils
Masses of lymphatic tissue in back of the oropharynx
toxin
poison; protein produced by certain bacteria, animals, or plants
immun/o
protection
lymphaden/o
lymph node
ana-
again, anew
inter-
between
Reverse transcriptase inhibitors (RTI)
inhibit enzyme called reverse transcriptase
Protease inhibitor
inhibit viral proteolytic enzyme
HAART (highly active anti-removal therapy)
comb. of RTI and Protease inhibitors
Allergy
abnormal sensitivity acquired by exposure to antigen
lymphoma
malignant tumor of the lymph nodes and lymph tissue
multiple myeloma
malignant tumor of bone marrow cells
thymoma
tumor of the thymus gland
CD4+ cell count
measures the # of CD4+ T cells in the blood stream wiht pts w/ AIDS
ELISA test
detects anti-HIV antibodies; western blot given as follow up
immunoelectrophoresis
separates immunoglobuins
Viral load test
measures the amount of AIDS virus (HIV) in bloodstream
AIDS
acquired immunodeficiency syndrome
CD4+ cell
helper T cell
CD8+ cell
cytotoxic T cell
CMV
cytomegalovirus
Crypto
Cryptococcus
ELISA
enzyme linked immunosorbent assay
G-CSF
Granulocyte colony- stimulating factor
GM-CSF
granulocyte- macrophage colony- stimulating factor
Histo
histoplasmosis
HIV
human immunodeficiency virus
HSV
herpes simplex virus
IL38 to IL5
interleukins
KS
kaposi sarcoma
MAI
myobacterium avium-intracellulare complex
MoAb
Monoclonal antibody
NHL
Non-hodgkin lymphoma
PCP
pneumocystic pneumonia
PI
protease inhibitor
RTI
reverse transcriptase inhibitor
Toxo
toxoplasmosis