Chp 13- Blood Lymphatic and Immune Flashcards
Type A
A antigen and B antibody
Type B
B antigen A antibody
Type AB
A and B antigen, no antibodies (universal recipient)
Type O
no A or B antigens and both anti-A and anti-B antibodies (universal donor)
Rh factor
positive and negative
- antigen on RBCs
albumin
protein in blood; maintains the proper amount of water in blood
Antibody (Ab)
specific protein produced by the lymphocytes in response to bacteria, viruses, or other antigens
antigen
a substance that stimulates production of an antibody
basophil
white blood cell that contains granules that stain blue
coagulation
blood clotting
colony-stimulating factor (CSF)
protein that stimulates growth of white blood cells
differentiation
the change in structure and function of a cell as it matures; specialization
electrophoresis
method of separating serum proteins by electrical charge and size
eosinophil
white blood cell that contains granules that stain red
erthroblasts
an immature red blood cell
erythrocyte
red blood cell
erythroprotein (EPO)
hormone secreted by kidneys that stimulates red blood cell formation
Fibrin
protein that forms the basis of a blood clot
fibrinogen
plasma protein that converted to fibrin on the clotting process
globulin
plasma protein
granulocyte
white blood cell with numerous dark-staining granules
hematopoietic stem
cell in bone marrow that gives rise to all types of blood cells
hemoglobin
blood protein containing iron; carries oxygen in red blood cells
hemolysis
breakdown of RBCs
heparin
an anticoagulant found in blood and tissue cells
immune reaction
response of immune system to foreign invasion
immunoglobulin
a protein with antibody activity
leukocyte
WBC
lymphocyte
mononuclear leukocyte that produces antibodies
macrophage
monocyte that migrates from blood to tissue spaces; as a phagocyte, engulfs foreign material and debris; destroys worn out RBS
Megakaryocyte
large platelet precursor cell found in the bone marrow
monocyte
leukocyte with one large nucleus; engulfs foreign material and debris; becomes macrophage
mononuclear
pertaining to cell (leukocyte) with single round nucleus
myeloblast
immature bone marrow that gives rise to granulocytes
neutrophil
granulocytic leukocyte formed in bone marrow; polymorphonuclear leukocyte
plasma
liquid portion of blood; contains water, protein, salts, nutrients, lipids, hormones, vitamins
plasmapheresis
Removal of plasma from withdrawn blood by centrifuge
platelet
small blood fragment important in clotting
polymorphonuculear
pretaining to WBC with multi-shaped nucleus; neutrophil
prothrombin
plasma protein; converted to thrombin in clotting process
reticulocyte
immature erythrocyte
serum
plasma minus clotting proteins and cells
stem cell
unspecialized cell that gives rise to mature, specialized forms
thormbin
emzyme that converts fibrinogen to fibrin during coagulation
thrombocyte
platelets
bas/o
base
chrom/o
color
coagul/o
clotting
cyt/o
cell
eosin/o
red, dawn, rosy
erythro/o
red
granul/o
granules
hem/o
blood
hemat/o
blood
hemoglobin/o
hemoglobin
is/o
same/equal
kary/o
nucleus
leuk/o
white
mon/o
single
morhp/o
shape, form
myel/o
bone marrow
neutr/o
neutral
nucle/o
nucleus
phag/o
eat, swallow
poikil/o
varied, irregular
sider/o
iron
spher/o
globe, round
thromb/o
clot
-apheresis
seperation/ takeaway
-oid
resembling
-osis
disease
-phoresis
transmission
anemia
deficiency in erythrocytes or hemoglobin
Aplastic anemia
bone marrow cannot make enough new blood cells for your body to work normally
hemolytic anemia
red blood cells are destroyed faster than they can be made
pernicious anemia
red blood cells that occurs when the intestines cannot properly absorb vitamin B12
sickle cell anemia
hereditary disorder of abnormal hemoglobin producing sickle shape eryhtocytes and hemolysis
thalassemia
inherited blood disorder caused when the body doesn’t make enough, leading to hypochromia
hemochromatosis
excess iron deposits throughout the body
polycythemia vera
general increase in RBC
hemophilia
excessive bleeding caused by hereditary lack of factors VIII and IX necessary for blood clotting. patients often bleed into weight-bearing joints, especially the ankles and knees
purpura
multiple pinpoint hemorrhages and accumulation of blood under the skin
leukemia
increase in cancerous white blood cells
granulocytosis
abnormal increase in granulocytes in blood
mononucleosis
infectious disease marked by increased numbers of mononuclear leukocytes and enlarged cervical lymph nodes
multiple myeloma
malignant neoplasm of bon marrow.
apheresis
separation of blood into component parts and removal of a select part from the blood
blood transfusion
whole blood or cells taken from a donor and infused into a patient
bone marrow biopsy
microscopic examination of core bone marrow removed with a needle
hematopoietic stem cell transplantation
peripheral stem cells from a compatible donor administered into a recipient
ABMT
autologous bone marrow transplantation
ABO
four main blood types - A, B, O, AB
ALL
acute lymphoid leukemia
AML
Acute myeloid leukemia
ANC
Absolute neutrophil count
ASCT
autologous stem cell transplantation
banda
immature white blood cells (granulocytes)
Baso
Basophils
BMT
bone marrow transplantation
CBC
complete blood count
CLL
Chronic lymphoid leukemia
CML
Chronic myeloid leukemia
DIC
Disseminated intravascular coagulation
diff
differential count (WBC)
EBV
Epstein-Barr virus
eos
eosinophiles
EPO
erythroprotein
ESR
Erythrocyte sedimentation rate
G-CSF
granulocyte colony-stimulating factor
GM-CSF
granulocyte-macrophage colony-stimulating factor
GVHD
graft-versus-host disease
HCL
hairy cell leukemia
Hct
hematocrit
Hgh, HGB
hemoglobin and hematocrit
HLA
human leukocyte antigen
IgS, IgD, IgE, IgG, IgM
immunoglobulins
ITP
idiopathic thromocytic purpura
lymphs
lymphocytes
MCH
mean corpuscular hemoglobin
MCHC
mean corpuscular hemoglobin concentration
MCV
mean corpuscular volume
MDS
myelodysplastic syndrome
mono
monocyte
Polys, PMNs, PMNLs
polymorphonuclear leukocytes
PT, pro time
prothrombin time
PTT
partial thromboplastin time
sed rate
erythrocyte sedimentation rate
segs
segmented, mature WBCs
SMAC
sequential Multiple Analyzer Computer
WNL
within normal limits