Chorea

Question 1

What are the 2 main diseases that cause chorea?

Answer 1

Huntingtons

Sydenham’s chorea

Question 2

Define chorea.

Answer 2

A neurological disorder characterised by jerky involuntary movements affecting especially the shoulders, hips, and face.
(Dance-like)

Question 3

What drug can treat chorea in huntingtons and how does it work?

Answer 3

Tetrabenzine (vesicular monoamine transporter)

Limits dopamine vesicle packaging and release

Question 4

What disease is sydenhams chorea associated with?

Answer 4

Rheumatic fever

Question 5

How long after rheumatic fever starts does sydenhams chorea occur?

Answer 5

Up to 6 months after

Question 6

What is the main group that sydenhams chorea affects?

Answer 6

Girls between 5-15

Developing world

Question 7

What are the 3 common symptoms of sydenham’s chorea?

Answer 7

Widespread chorea (duh)
Behavioural disturbance
Obsessive compulsive symptoms

Question 8

How long does sydenham’s chorea last for?

Answer 8

Up to 6 months