*cholinergic blocking drugs Flashcards

1
Q

what is the general MOA of cholinergic blocking drugs

A

block or inhibit the actions of acetylcholine

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2
Q

what drug class do atropine and scopolamine belong to

A

natural plant alkaloids

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3
Q

what drug class do glycopyrrolate, oxybutynin and tolterodine belong to

A

synthetic and semisynthetic

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4
Q

what are the typical drug effects of colinergic blocking drugs

A

increased HR, bronchial dilation, dry mucous membranes

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5
Q

what do high doses of cholinergic blocking drugs do

A

increased heart rate

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6
Q

what do low doses of cholinergic blocking drugs do

A

slow HR

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7
Q

what is atropine primarily used for

A

cardiovascular disorders

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8
Q

what is used to treat cholinergic blocking toxicity

A

physostigmine

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9
Q

what does amantadine, antihistamines, phenothiazines and digoxin do when taking cholinergic blocking drugs

A

increase the effects of the cholinergic blocking drugs

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10
Q

what does glycopyrrolate treat

A

preoperative reduction of salivation

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11
Q

what does oxybutynin treat

A

overactive bladder

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12
Q

what does scopolamine treat

A

motion sickness

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13
Q

what does tolterodine treat

A

urinary urgency, incontinence

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