*adrenal drugs Flashcards
what catecholamines does the adrenal medulla secrete
epinephrine and norepinephrine
what corticosteriods does the adrenal cortex secrete
Glucocorticoids and mineralocorticoids (aldosterone)
what does over secretion of adrenocortical hormones cause
Cushings syndrome
what does under secretion of adrenocotrical hormones cause
Addisons disease
drug examples of glucocorticoids
hydrocortisone, methylprednisolone, prednisone
drug example of mineralcorticoids
fludrocortisone 21
drug example of adrenal steroid inhibitor
ketoconazole
corticosteroid MOA
modify enzyme activity
glucocorticoid MOA
inhibit or help control inflammatory and immune responses
glucocorticoids route of administration
inhalation, nasal or topical (ear, eye and skin)
what body systems do adrenal drugs effect
cardiovascular, nervous, endocrine, GI, integumentary, MS, ocular
what is the most commonly used glucocorticoid
prednisone
what is the most commonly used injectable glucocorticoid
methylprednisolone