*antiepileptics Flashcards
what are the stages of a seizure
ora, ictal, post ictal
what is the drug of choice for immediate treatment of status epileptics
diazepam
what serum concentrations of drugs correlate better with seizure control than vampiric acid, ethosuximide and clonazepam
phenytoin, pentobarbital, carbamazepine and primidone
what are the drug classes
barituates, hydantoins, iminostilbenes plus valproic acid, second and third get antieptileptics
what is the mechanism of action of antiepileptics
reduces nerves ability to be stimulated, suppresses nerve transmission of nerve impulses and decreases the speed of nerve impulses
what effect does dilantin have on fetuses
congenital spinal malformations
which antieptileptic increases warfarin levels
phenytoin
what anti epileptic increases metabolism of acetaminophen
carbamazepine
what drug displaces vampiric acid from protein binding which increases serum levels
aspirin
which drugs have a low therapeutic index requiring lab drug monitoring
phenytoin, vampiric acid, phenobarbital and carbamazepine
what must phenytoin sodium be diluted with to be administer IV
normal saline
what is type of needle must be used to administer phenytoin sodium
filter needle
what is the mechanism of action of gabapentin
gaba is a neurotransmitter than inhibits brain activity
what drug is safe is to take with pregnancy
lamotrigine
what drug is structurally similar to gabapentin
pregabalin
