acid controlling drugs

Question 1

what is the normal ph of the stomach

Answer 1

1-4

Question 2

what is triple therapy for H. pylori

Answer 2

it is a 7-14 day course of proton pump inhibitors, clarithromycin and either amoxicillin or metronidrazole

Question 3

what is quadruple therapy for H. pylori

Answer 3

a 7-14 day course of proton pump inhibitors, bismuth subsalicylate and either tetracycline and metronidazole

Question 4

what are the types of acid controlling drugs

Answer 4

antacids
H2 agonists
PPIs

Question 5

what is the mechanism of action of antacids

Answer 5

basic compounds used to neutralize stomach acid, but it does not effect the production

Question 6

what drug do many antacids contian

Answer 6

antiflatulent drug: simethicone and magnesium

Question 7

what does magnesium in antacids do

Answer 7

prevents the constipating effects of aluminum and calcium

Question 8

what are the examples of antacids

Answer 8

aluminum hydroxide, magnesium hydroxide, simethicone, combo: aluminum hydroxide and magnesium hydroxide

Question 9

what is the drug example for aluminum salts

Answer 9

combo: aluminum and magnesium

Question 10

what is the drug example for magnesium salts

Answer 10

magnesium hydroxide and mineral oil

Question 11

is magnesium salts, calcium salts or aluminum salts used for pt with renal failure

Answer 11

aluminum salts. more easily exerted

Question 12

what is the drug example for calcium salts

Answer 12

calcium carbonate and simethicone

Question 13

what class is sodium bicarbonate

Answer 13

antacid

Question 14

what is the example for antiflatulants

Answer 14

simethicone

Question 15

what class of drugs cause decreased absorption of other drugs

Answer 15

antacids

Question 16

H2 receptor agonists drug examples

Answer 16

ranitidine and famotidine

Question 17

H2 agonists MOA

Answer 17

competitively block the H2 receptor of acid producing parietal cells which increases the pH of the stomach

Question 18

what drug class inhibits the absorption of drugs that require an acidic gastrointestinal environment for absorption

Answer 18

H2 receptor agonists

Question 19

examples of proton inhibitor drugs

Answer 19

lansoprazole, omeprazole, pantoprazole

Question 20

proton pump inhibitor MOA

Answer 20

blocks the movement of hydrogen ions from the parietal cells into the stomach which blocks all gastric acid secretions

Question 21

examples of miscellaneous acid controlling drugs

Answer 21

sucralfate, misoprostol, simethicone

Question 22

what is sucralfate used for

Answer 22

ulcers in the stomach

Question 23

what does misoprostol do

Answer 23

enhances local production of mucus or bicarbonate