Child Allergy Flashcards

1
Q

how does food allergy develop

A

through sensitisation

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2
Q

what is allergy

A

IgE specific to allergen
production of mast cells
degranulation
histamine, tryptase and hydrolasde

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3
Q

what is the effects of histamine

A

bronchial smooth muscle contraction
wheeze
vasodilation-redness, fainting
pain and itching

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4
Q

does allergy have a genetic influence

A

yes
parental atopy
concordance for allergy int twins
hyigee

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5
Q

what is the presentation of allwrgy

A
rapid onset 
histamine mediated reactions
urticaria
itching 
pallor 
sweating 
improvement with antihistamines
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6
Q

what can cause a histamine based reaction

A
food-egg milk, peanut, soya
contact
environmental agent
no cause 
drugs
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7
Q

what is supporting evidence of allergy

A
previous reactions
atopy 
family history 
response to treatment 
has asthma
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8
Q

what are the investigations

A

skin prick test
specific IgE
oral food challenge

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9
Q

what Is anaphylaxis

A

laryngeal oedema
hypotension
collapse
bronchospasm

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10
Q

what do you treat anaphylaxis

A

adrenaline pen
epipen
education at home and school

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11
Q

what is the effect of adrenaline pen

A

reverses peripheral vasodilation
increases peripheral vascular reisstanc e
causes bronchodilator

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