Child Allergy Flashcards
how does food allergy develop
through sensitisation
what is allergy
IgE specific to allergen
production of mast cells
degranulation
histamine, tryptase and hydrolasde
what is the effects of histamine
bronchial smooth muscle contraction
wheeze
vasodilation-redness, fainting
pain and itching
does allergy have a genetic influence
yes
parental atopy
concordance for allergy int twins
hyigee
what is the presentation of allwrgy
rapid onset histamine mediated reactions urticaria itching pallor sweating improvement with antihistamines
what can cause a histamine based reaction
food-egg milk, peanut, soya contact environmental agent no cause drugs
what is supporting evidence of allergy
previous reactions atopy family history response to treatment has asthma
what are the investigations
skin prick test
specific IgE
oral food challenge
what Is anaphylaxis
laryngeal oedema
hypotension
collapse
bronchospasm
what do you treat anaphylaxis
adrenaline pen
epipen
education at home and school
what is the effect of adrenaline pen
reverses peripheral vasodilation
increases peripheral vascular reisstanc e
causes bronchodilator