chapters 1-4: intro to microbio & chemical properties Flashcards
microorganisms
(aka microbes) organisms too small to be see with the unaided eye
pathogen
disease producing organism
what is a prokaryote?
an organism without a membrane bound nucleus; “prenucleus”
characteristics of bacteria
prokaryote, single-celled, peptidoglycan cell walls, divide via binary fission; may swim by using appendages (flagella)
characteristics of archaea
prokaryote, lack peptidoglycan cell walls (may lack cell wall entirely), often live in extreme environments, generally not known to cause disease in humans
Ex) methanogens, extreme halophiles, extreme thermophiles
what is a eukaryote?
an organism with a membrane bound nucleus
characteristics of fungi
eukaryote, chitin cell walls, absorb organic chemicals for energy
Ex) yeasts - unicellular
molds (mycelia & hyphae) & mushrooms - multicellular
characteristics of protozoa
eukaryote, absorb or ingest organic chemicals, may be motile via pseudopods, cilia, or flagella, free living or parasitic, reproduce sexually or asexually
characteristics of viruses
acellular, consist of DNA or RNA core, core is surrounded by protein coat; are replicated only when they are in a living host cell
who reported that “living things are composed of little boxes / ‘cork cells’”?
Robert Hooke
cell theory
all living things are composed of cells
who discovered first microbes as “animalcules” (microscopic animals)
Anton van Leeuwenhoek
spontaneous generation
hypothesis that life arises from nonliving matter; a “vital force” is necessary for life
biogenesis
[Rudolf Virchow] hypothesis that living cells arise only from preexisting cells
germ theory of disease
uses Koch’s postulates (experimental steps) to demonstrate that a specific microbe causes a specific disease
miasma theory of disease
obsolete theory that diseases (cholera, black death) come from a noxious form of “bad air” or from rotting organic matter
significance of Redi’s “jar of meats” experiment
debate over spontaneous generation; covered jars and sealed jars did not get maggots while opened jars did
significance of Pasteur’s “long necked flasks” experiment
disproved spontaneous generation by using s-shaped flasks to keep microbes out but let air in; when the broth was not sealed, there was microbial growth; when the broth was sealed, there was no microbial growth; shows that microbes originate in air or fluids
Koch’s postulates
1) microorganism must be observed in every case of the disease
2) it must be isolated and grown in pure culture
3) the pure culture, when inoculated in an animal, must reproduce the disease
4) microorganism must be recovered from diseased animal
“magic bullet” and who discovered it
[Paul Ehrlich] synthetic drug that could destroy a pathogen without harming the host;
- synthetic arsenic drug to treat syphilis = salvarsan
who inoculated a person with cowpox virus in 1796 (beginning of vaccinations)?
Edward Jenner
who created the first antibiotic, penicillin on accident by the Penicillium fungus?
Alexander Fleming
taxonomy
[Linnaeus] classification of organisms by scientific nomenclature (genus and specific epithet); italicized and genus is capitalized
protons
subatomic particle with positive charge; makes up nucleus of atom
neutrons
subatomic particle with no electrical charge; makes up nucleus of atom
electrons
subatomic particle with negative charge
chemical reaction
involves the making or breaking of bonds between atoms
endergonic reactions
absorbs energy
exergonic reactions
releases energy
element
pure element which cannot be broken down by chemical means
isotope
variants of a chemical element which differ in neutron numbers
valence
the number of missing or extra electrons in the outermost shell
ionic bond
attractions between ions of opposite charge; one atom loses electrons and one atom gains electrons
ions
charged atoms that have gained or lost electrons
covalent bond
two atoms share one or more pairs of electrons
polar
unequal distribution of electrons; “pull”
nonpolar
equal distribution of electrons; “no pull”
properties of water
- temperature buffer (absorbs heat)
- great solvent: polar substances undergo dissociation in water, forming solutes
solute
a substance dissolved in another substance
solvent
substance that dissolves a solute
acid
substances that dissociate into one or more hydrogen atoms and one or more negative ions
base
substances that dissociate into one or more hydroxide ions and one or more positive ions
pH
concentration of H+ in a solution