Chapter 9 - Development of the Nervous System Flashcards
Zygote
The cell formed from the amalgamation of a sperm cell and an ovum
Totipotent
Capable of developing into any type of body cell
Pluripotent
Cells that can develop into many, but not all, classes of body cells
Multipotent
Capable of developing into different cells of only one class of cells (e.g., different kinds of blood cells)
Unipotent
Cells that can develop into only one type of cell
Stem cells
Cells that have an almost unlimited capacity for self-renewal and the ability to develop into many different types of cells
Neural plate
A small patch of ectodermal tissue on the dorsal surface of the vertebrate embryo, from which the neural groove, the neural tube, and, ultimately, the mature nervous system develop
Mesoderm layer
The middle of the three cell layers in the developing embryo
Neural tube
The tube that is formed in the vertebrate embryo when the edges of the neural groove fuse and that develops into the central nervous system
Neural proliferation
The rapid increase in the number of neurons that follows the formation of the neural tube
Ventricular zone
The region adjacent to the ventricle in the developing neural tube
Subventricular zone
A region adjacent to the ventricular zone; the ventricular zone is adjacent to the ventricles
Radial glial cells
Glial cells that exist in the neural tube during the period of neural migration and that form a network along which radial migration occurs. Some radial glial cells are stem cells
Migration
The movement of cells from their site of creation in the ventricular zone of the neural tube to their appropriate target location
Radial migration
Movement of cells in the developing neural tube from the ventricular zone in a straight line outward toward the tube’s outer wall
Tangential migration
Movement of cells in the developing neural tube in a direction parallel to the tube’s walls
Somal translocation
One of two major modes of neural migration, in which an extension grows out from the undeveloped neuron and draws the cell body up into it
Radial-glia-mediated migration
A type of migration in which the developing cell uses the long process that extends from each radial-glia cell as a sort of rope along which it pulls itself up and away from the ventricular zone.
Radial-glia-mediated migration allows a cell to migrate in only a radial fashion.
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